Interactor 1: ABCA1 (O95477)
Phospholipid-transporting ATPase ABCA1 (EC 7.6.2.1) (ATP-binding cassette sub-family A member 1) (ATP-binding cassette transporter 1) (ABC-1) (ATP-binding cassette 1) (Cholesterol efflux regulatory protein)
Gene: ABCA1
Interactor 2: NR1H2 (P55055)
Oxysterols receptor LXR-beta (Liver X receptor beta) (Nuclear receptor NER) (Nuclear receptor subfamily 1 group H member 2) (Ubiquitously-expressed nuclear receptor)
Gene: NR1H2
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.66 | 0.60 | 0.633 |
The method score is based on:
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | - |
| Common GO terms | GO:0010745 - negative regulation of macrophage derived foam cell differentiation GO:0010875 - positive regulation of cholesterol efflux GO:0010887 - negative regulation of cholesterol storage GO:0042632 - cholesterol homeostasis GO:0051117 - ATPase binding and 1 others more... |
| Homologous interactions | 3 |
Homologous interactions
Color coding for hit scores 
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Last updated: 15 Jul 2024
