HitPredict

Interactor 1: CBX6 (O95503)
Chromobox protein homolog 6
Gene: CBX6

Interactor 2: NCOR2 (Q9Y618)
Nuclear receptor corepressor 2 (N-CoR2) (CTG repeat protein 26) (SMAP270) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (T3 receptor-associating factor) (TRAC) (Thyroid-, retinoic-acid-receptor-associated corepressor)
Gene: NCOR2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	21282530
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0000785 - chromatin GO:0003682 - chromatin binding GO:0005634 - nucleus GO:0005654 - nucleoplasm and 1 others more... GO:0016604 - nuclear body
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 412 Hs			1 2514
+	Hs
		261433 CBX5_HUMAN (11-106): 3.1e-28: 111: 29.17		NCOR1_HUMAN (1-2514): 9.88e-128: 453: 34.38
+	Hs
		261495 CBX3_HUMAN (9-121): 1.26e-25: 104: 24.56		NCOR1_HUMAN (1-2514): 9.88e-128: 453: 34.38
+	Hs
		949908 CBX1_HUMAN (17-85): 6.16e-23: 97.1: 34.78		RCOR1_HUMAN (388-705): 2.51e-45: 174: 22.05
+	Hs
		1027333 CBX3_HUMAN (9-121): 1.26e-25: 104: 24.56		SRRM2_HUMAN (11-1905): 4.06e-30: 133: 8.95
+	Hs
		203821 SUV91_HUMAN (11-222): 8.35e-36: 137: 17.21		CABIN_HUMAN (722-1134): 2.25e-13: 78.9: 19.17
+	Hs
		800501 CBX5_HUMAN (11-106): 3.1e-28: 111: 29.17		CIC_HUMAN (7-2131): 8.47e-18: 93.5: 9.33
+	Hs
		1027214 CBX3_HUMAN (9-121): 1.26e-25: 104: 24.56		MINT_HUMAN (80-1321): 6.8e-20: 100: 8.11
+	Hs
		1027207 CBX3_HUMAN (9-121): 1.26e-25: 104: 24.56		CIC_HUMAN (7-2131): 8.47e-18: 93.5: 9.33