HitPredict

Interactor 1: KLF8 (O95600)
Krueppel-like factor 8 (Basic krueppel-like factor 3) (Zinc finger protein 741)
Gene: KLF8

Interactor 2: NFIA (Q12857)
Nuclear factor 1 A-type (NF1-A) (Nuclear factor 1/A) (CCAAT-box-binding transcription factor) (CTF) (Nuclear factor I/A) (NF-I/A) (NFI-A) (TGGCA-binding protein)
Gene: NFIA

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.55	0.60	0.578

Property	Details
Experiments	35140242
Identification Methods	proximity labelling technology, pull down, anti tag coimmunoprecipitation
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000785 - chromatin GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific GO:0005654 - nucleoplasm GO:0006357 - regulation of transcription by RNA polymerase II
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 359 Hs			1 509
+	Hs
		1018285 KLF12_HUMAN (44-356): 6.24e-85: 264: 42.58		NFIA_HUMAN (1-509): 1.11e-161: 470: 100.00
+	Hs
		316771 KLF8_HUMAN (1-356): 5.7e-92: 281: 100.00		NFIC_HUMAN (3-509): 2.94e-130: 390: 57.61
+	Hs
		135061 KLF8_HUMAN (1-356): 5.7e-92: 281: 100.00		NFIB_HUMAN (1-413): 8.24e-127: 378: 61.41
+	Hs
		884143 KLF3_HUMAN (22-356): 2.98e-51: 175: 34.19		NFIA_HUMAN (1-509): 1.11e-161: 470: 100.00
+	Hs
		204171 KLF4_HUMAN (105-356): 4.72e-49: 174: 32.56		NFIA_HUMAN (1-509): 1.11e-161: 470: 100.00
+	Hs
		135179 KLF12_HUMAN (44-356): 6.24e-85: 264: 42.58		NFIB_HUMAN (1-413): 8.24e-127: 378: 61.41
+	Hs
		1018221 KLF5_HUMAN (267-356): 1.18e-41: 152: 78.89		NFIA_HUMAN (1-509): 1.11e-161: 470: 100.00
+	Hs
		1018262 KLF16_HUMAN (274-356): 1.56e-29: 115: 61.45		NFIA_HUMAN (1-509): 1.11e-161: 470: 100.00
+	Hs
		443161 KLF3_HUMAN (22-356): 2.98e-51: 175: 34.19		NFIC_HUMAN (3-509): 2.94e-130: 390: 57.61
+	Hs
		135101 KLF3_HUMAN (22-356): 2.98e-51: 175: 34.19		NFIB_HUMAN (1-413): 8.24e-127: 378: 61.41
+	Hs
		741052 ZEB1_HUMAN (278-357): 3.11e-13: 72.9: 29.17		NFIX_HUMAN (1-508): 9.66e-154: 449: 67.32
+	Hs
		443241 KLF16_HUMAN (274-356): 1.56e-29: 115: 61.45		NFIC_HUMAN (3-509): 2.94e-130: 390: 57.61
+	Hs
		135155 KLF16_HUMAN (274-356): 1.56e-29: 115: 61.45		NFIB_HUMAN (1-413): 8.24e-127: 378: 61.41
+	Hs
		443260 ZKSC7_HUMAN (71-142): 4.3e-09: 60: 10.96		NFIC_HUMAN (3-509): 2.94e-130: 390: 57.61
+	Hs
		204195 KLF4_HUMAN (105-356): 4.72e-49: 174: 32.56		KMT2C_HUMAN (183-506): 4.24e-10: 64.9: 9.12
+	Hs
		1046715 KLF5_HUMAN (267-356): 1.18e-41: 152: 78.89		KMT2C_HUMAN (183-506): 4.24e-10: 64.9: 9.12
+	Hs
		1243850 KLF15_HUMAN (272-356): 1.38e-31: 125: 63.53		KMT2C_HUMAN (183-506): 4.24e-10: 64.9: 9.12