HitPredict

Interactor 1: PCNT (O95613)
Pericentrin (Kendrin) (Pericentrin-B)
Gene: PCNT

Interactor 2: SPTN1 (Q13813)
Spectrin alpha chain, non-erythrocytic 1 (Alpha-II spectrin) (Fodrin alpha chain) (Spectrin, non-erythroid alpha subunit)
Gene: SPTAN1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.48	0.60	0.541

Property	Details
Experiments	35914814
Identification Methods	two hybrid, two hybrid fragment pooling approach
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005516 - calmodulin binding GO:0005829 - cytosol GO:0016020 - membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 3336 Hs			1 2472
+	Hs
		164543 PCNT_HUMAN (1-3336): 0: 718: 100.00		SPTN2_HUMAN (141-1932): 1.25e-65: 250: 20.41
+	Hs
		969584 CENPE_HUMAN (1328-3305): 2.89e-65: 250: 10.28		SPTN1_HUMAN (1-2472): 0: 714: 100.00
+	Hs
		317230 PCNT_HUMAN (1-3336): 0: 718: 100.00		SPTB2_HUMAN (2-1043): 1.4e-42: 174: 20.52
+	Hs
		317231 PCNT_HUMAN (1-3336): 0: 718: 100.00		DYST_HUMAN (5-2410): 1.41e-35: 152: 10.59
+	Hs
		166650 PCNT_HUMAN (1-3336): 0: 718: 100.00		CE290_HUMAN (808-2443): 1.12e-32: 142: 10.61
+	Hs
		522612 MYH7_HUMAN (2483-3316): 1.1e-33: 146: 12.07		SPTN1_HUMAN (1-2472): 0: 714: 100.00
+	Hs
		317252 PCNT_HUMAN (1-3336): 0: 718: 100.00		PLEC_HUMAN (16-1253): 4.4e-31: 137: 9.18
+	Hs
		317377 PCNT_HUMAN (1-3336): 0: 718: 100.00		MACF1_HUMAN (9-1261): 9.1e-18: 93.6: 12.48
+	Hs
		360660 CP250_HUMAN (1630-3336): 3.41e-53: 210: 10.43		SPTA1_HUMAN (1-2472): 2.98e-159: 552: 54.81
+	Dm
		527099 LVA_DROME (1967-3211): 1.36e-32: 142: 10.43		SPTCA_DROME (3-2472): 1.26e-174: 598: 63.92
+	Dm
		962674 LVA_DROME (1967-3211): 1.36e-32: 142: 10.43		SPTCB_DROME (539-2297): 1.26e-67: 257: 20.15
+	Hs
		974137 CP250_HUMAN (1630-3336): 3.41e-53: 210: 10.43		DYST_HUMAN (5-2410): 1.41e-35: 152: 10.59
+	Hs
		828575 CENPE_HUMAN (1328-3305): 2.89e-65: 250: 10.28		CENPF_HUMAN (1723-2444): 8.12e-13: 77: 9.28
+	Hs
		1034577 GOGA4_HUMAN (2170-3252): 2.83e-32: 141: 10.17		GOGB1_HUMAN (2-1186): 3.65e-38: 160: 10.57
+	Hs
		166696 CE290_HUMAN (1764-3201): 5.48e-34: 147: 10.55		DYST_HUMAN (5-2410): 1.41e-35: 152: 10.59
+	Hs
		166640 CE290_HUMAN (1764-3201): 5.48e-34: 147: 10.55		CE290_HUMAN (808-2443): 1.12e-32: 142: 10.61
+	Hs
		1059212 GOGB1_HUMAN (2204-3322): 8.52e-25: 117: 9.50		GOGB1_HUMAN (2-1186): 3.65e-38: 160: 10.57
+	Dm
		1182584 LVA_DROME (1967-3211): 1.36e-32: 142: 10.43		Q7KV70_DROME (1-592): 1.99e-24: 115: 29.61
+	Hs
		1061289 NUMA1_HUMAN (43-1227): 1.53e-33: 145: 10.92		MACF1_HUMAN (9-1261): 9.1e-18: 93.6: 12.48
+	Hs
		110636 MYH9_HUMAN (2690-3313): 1.18e-18: 96.7: 9.89		H3BPE1_HUMAN (9-1261): 4.01e-18: 94.7: 12.35