Interactor 1: NFAC1 (O95644)
Nuclear factor of activated T-cells, cytoplasmic 1 (NF-ATc1) (NFATc1) (NFAT transcription complex cytosolic component) (NF-ATc) (NFATc)
Gene: NFATC1

Interactor 2: CREB1 (P16220)
Cyclic AMP-responsive element-binding protein 1 (CREB-1) (cAMP-responsive element-binding protein 1)
Gene: CREB1

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.64 1.00 0.802

The method score is based on:

Property Details
Experiments 25609649, 27637333
Identification Methods affinity chromatography technology, pull down, tandem affinity purification
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains RHD_DNA_bind~bZIP_1
Common GO terms GO:0000785 - chromatin
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001228 - DNA-binding transcription activator activity, RNA polymerase II-specific
GO:0003700 - DNA-binding transcription factor activity
and 7 others

more...

Homologous interactions 3

Homologous interactions

Color coding for hit scores

1 943
Hs

1 327
+ Hs
+ Hs
+ Dm

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Last updated: 15 Jul 2024