Protein: DUSP2
Dual specificity protein phosphatase 2 (EC 3.1.3.16) (EC 3.1.3.48) (Dual specificity protein phosphatase PAC-1)

Gene: DUSP2
Organism: Homo sapiens
Interactions: 79
UniProt ID: Q05923

Gene Ontology (top 5):
GO:0001706 - endoderm formation
GO:0004721 - phosphoprotein phosphatase activity
GO:0004722 - protein serine/threonine phosphatase activity
GO:0004725 - protein tyrosine phosphatase activity
GO:0005634 - nucleus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

703549

MK01
Mitogen-activated protein kinase 1

4

20

Small-scale

0.881

High

1052830

MK14
Mitogen-activated protein kinase 14

2

20

High-throughput

0.754

High

997665

CSK21
Casein kinase II subunit alpha

1

5

Small-scale

0.724

High

400697

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

7

High-throughput

0.618

High

724678

MK04
Mitogen-activated protein kinase 4

1

20

High-throughput

0.618

High

858635

MP2K3
Dual specificity mitogen-activated protein kinase kinase 3

1

8

High-throughput

0.618

High

902920

DUS3
Dual specificity protein phosphatase 3

1

18

High-throughput

0.618

High

1052822

DUSP2
Dual specificity protein phosphatase 2

1

15

High-throughput

0.618

High

1052829

MK11
Mitogen-activated protein kinase 11

1

20

High-throughput

0.618

High

1052838

ANKH1
Ankyrin repeat and KH domain-containing protein 1

1

6

High-throughput

0.618

High

691716

MK03
Mitogen-activated protein kinase 3

1

20

Small-scale

0.575

High

1052847

UBP7
Ubiquitin carboxyl-terminal hydrolase 7

1

6

High-throughput

0.501

High

174189

SYN3
Synapsin-3

1

2

High-throughput

0.489

High

605517

SYN1
Synapsin-1

1

5

High-throughput

0.489

High

1052846

SYN2
Synapsin-2

1

3

High-throughput

0.489

High

838071

STAT1
Signal transducer and activator of transcription 1-alpha/beta

1

0

Small-scale

0.480

High

124767

AIP
AH receptor-interacting protein

1

5

High-throughput

0.479

High

220900

XPOT
Exportin-T

1

7

High-throughput

0.479

High

272646

BRE1B
E3 ubiquitin-protein ligase BRE1B

1

8

Small-scale

0.479

High

289508

U520
U5 small nuclear ribonucleoprotein 200 kDa helicase

1

5

High-throughput

0.479

High

325803

UBR5
E3 ubiquitin-protein ligase UBR5

1

2

High-throughput

0.479

High

543188

UBL4A
Ubiquitin-like protein 4A

1

4

High-throughput

0.479

High

584749

NDKA
Nucleoside diphosphate kinase A

1

6

High-throughput

0.479

High

623298

RO52
E3 ubiquitin-protein ligase TRIM21

1

3

Small-scale

0.479

High

627319

AT2B1
Plasma membrane calcium-transporting ATPase 1

1

3

High-throughput

0.479

High

666089

PPAC
Low molecular weight phosphotyrosine protein phosphatase

1

1

High-throughput

0.479

High

715554

MARCS
Myristoylated alanine-rich C-kinase substrate

1

1

Small-scale

0.479

High

716422

PRDX5
Peroxiredoxin-5, mitochondrial

1

3

High-throughput

0.479

High

841703

LPPRC
Leucine-rich PPR motif-containing protein, mitochondrial

1

10

High-throughput

0.479

High

890454

RBP2
E3 SUMO-protein ligase RanBP2

1

4

High-throughput

0.479

High

907391

UBP11
Ubiquitin carboxyl-terminal hydrolase 11

1

5

High-throughput

0.479

High

927249

ATX1
Ataxin-1

1

5

Small-scale

0.479

High

930295

AAKG1
5'-AMP-activated protein kinase subunit gamma-1

1

3

Small-scale

0.479

High

960404

PSME3
Proteasome activator complex subunit 3

1

4

High-throughput

0.479

High

988307

RAC1
Ras-related C3 botulinum toxin substrate 1

1

1

Small-scale

0.479

High

992569

IF5A1
Eukaryotic translation initiation factor 5A-1

1

4

High-throughput

0.479

High

1008104

PRKDC
DNA-dependent protein kinase catalytic subunit

1

1

High-throughput

0.479

High

1050974

FAK1
Focal adhesion kinase 1

1

20

Small-scale

0.479

High

1052823

DPOE1
DNA polymerase epsilon catalytic subunit A

1

3

High-throughput

0.479

High

1052825

FKBP5
Peptidyl-prolyl cis-trans isomerase FKBP5

1

8

High-throughput

0.479

High

1052826

ESPL1
Separin

1

1

High-throughput

0.479

High

1052827

SMC1A
Structural maintenance of chromosomes protein 1A

1

4

High-throughput

0.479

High

1052828

TEBP
Prostaglandin E synthase 3

1

2

High-throughput

0.479

High

1052832

UBR4
E3 ubiquitin-protein ligase UBR4

1

5

High-throughput

0.479

High

1052833

ECM29
Proteasome adapter and scaffold protein ECM29

1

8

High-throughput

0.479

High

1052834

PRP8
Pre-mRNA-processing-splicing factor 8

1

2

High-throughput

0.479

High

1052835

SKI3
Superkiller complex protein 3

1

7

High-throughput

0.479

High

1052839

ASCC3
Activating signal cointegrator 1 complex subunit 3

1

5

High-throughput

0.479

High

1052841

NU133
Nuclear pore complex protein Nup133

1

1

High-throughput

0.479

High

1052844

GCN1
Stalled ribosome sensor GCN1

1

8

High-throughput

0.479

High

1052845

NU205
Nuclear pore complex protein Nup205

1

4

High-throughput

0.479

High

1052848

UB2E3
Ubiquitin-conjugating enzyme E2 E3

1

1

Small-scale

0.479

High

1052849

ABHEB
Putative protein-lysine deacylase ABHD14B

1

2

High-throughput

0.479

High

1052850

PARK7
Parkinson disease protein 7

1

5

High-throughput

0.479

High

1052854

ACAD9
Complex I assembly factor ACAD9, mitochondrial

1

2

High-throughput

0.479

High

1052855

FANCI
Fanconi anemia group I protein

1

1

High-throughput

0.479

High

1052856

VPS4A
Vacuolar protein sorting-associated protein 4A

1

8

High-throughput

0.479

High

1052857

DICER
Endoribonuclease Dicer

1

8

High-throughput

0.479

High

1052858

DCAF1
DDB1- and CUL4-associated factor 1

1

2

High-throughput

0.479

High

1052859

TELO2
Telomere length regulation protein TEL2 homolog

1

1

High-throughput

0.479

High

61102

T131L
Transmembrane protein 131-like

1

0

High-throughput

0.458

High

134015

IPO5
Importin-5

1

0

High-throughput

0.458

High

933621

PSMD4
26S proteasome non-ATPase regulatory subunit 4

1

0

Small-scale

0.458

High

1052824

EP300
Histone acetyltransferase p300

1

0

Small-scale

0.458

High

1052852

RPAP1
RNA polymerase II-associated protein 1

1

0

High-throughput

0.458

High

175015

SC16A
Protein transport protein Sec16A

1

1

High-throughput

0.437

High

317830

LTN1
E3 ubiquitin-protein ligase listerin

1

1

High-throughput

0.437

High

463068

YES
Tyrosine-protein kinase Yes

1

11

Small-scale

0.437

High

1052831

NU188
Nucleoporin NUP188

1

1

High-throughput

0.437

High

1052842

FACR1
Fatty acyl-CoA reductase 1

1

2

High-throughput

0.437

High

1052843

AP3S1
AP-3 complex subunit sigma-1

1

7

High-throughput

0.437

High

1052853

T126A
Transmembrane protein 126A

1

1

High-throughput

0.437

High

388844

APOH
Beta-2-glycoprotein 1

1

0

Small-scale

0.249

Low

727556

SC6A4
Sodium-dependent serotonin transporter

1

0

High-throughput

0.249

Low

1052836

MON2
Protein MON2 homolog

1

0

High-throughput

0.249

Low

1052837

ZN598
E3 ubiquitin-protein ligase ZNF598

1

0

Small-scale

0.249

Low

1052840

MIA40
Mitochondrial intermembrane space import and assembly protein 40

1

0

High-throughput

0.249

Low

1052851

THTPA
Thiamine-triphosphatase

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025