HitPredict

Interactor 1: EYA4 (O95677)
Eyes absent homolog 4 (EC 3.1.3.48)
Gene: EYA4

Interactor 2: HNF1B (P35680)
Hepatocyte nuclear factor 1-beta (HNF-1-beta) (HNF-1B) (Homeoprotein LFB3) (Transcription factor 2) (TCF-2) (Variant hepatic nuclear factor 1) (vHNF1)
Gene: HNF1B

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35140242
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 639 Hs			1 557
+	Hs
		318708 EYA4_HUMAN (1-639): 0: 650: 100.00		PITX2_HUMAN (181-482): 6.45e-28: 116: 13.68
+	Hs
		727502 EWS_HUMAN (103-334): 1.19e-32: 135: 17.21		HNF1B_HUMAN (1-557): 6.73e-147: 436: 100.00
+	Ce
		106218 EYA1_CAEEL (167-635): 6.6e-97: 308: 23.45		VAB3_CAEEL (84-486): 4.22e-58: 202: 13.86
+	Dm
		185814 EYA_DROME (35-639): 3.98e-143: 436: 38.00		PAX6_DROME (83-224): 9.32e-13: 73.2: 17.53
+	Hs
		727560 KMT2C_HUMAN (17-365): 1.05e-10: 67.3: 9.52		HNF1B_HUMAN (1-557): 6.73e-147: 436: 100.00
+	Hs
		727561 ARI1B_HUMAN (89-361): 6.56e-09: 61.5: 12.41		HNF1B_HUMAN (1-557): 6.73e-147: 436: 100.00
+	Ce
		112063 EYA1_CAEEL (167-635): 6.6e-97: 308: 23.45		UNC42_CAEEL (232-384): 2.06e-13: 72.7: 16.99
+	Hs
		595941 KMT2C_HUMAN (17-365): 1.05e-10: 67.3: 9.52		HNF1A_HUMAN (1-551): 2.16e-85: 279: 53.21
+	Hs
		620175 KMT2C_HUMAN (17-365): 1.05e-10: 67.3: 9.52		PAX7_HUMAN (84-479): 2.24e-58: 204: 15.58
+	Hs
		641482 KMT2C_HUMAN (17-365): 1.05e-10: 67.3: 9.52		PAX6_HUMAN (83-460): 3.74e-59: 204: 15.54
+	Hs
		941892 EWS_HUMAN (103-334): 1.19e-32: 135: 17.21		PITX1_HUMAN (144-427): 1.5e-33: 131: 16.44
+	Hs
		620176 ARI1B_HUMAN (89-361): 6.56e-09: 61.5: 12.41		PAX7_HUMAN (84-479): 2.24e-58: 204: 15.58
+	Hs
		641483 ARI1B_HUMAN (89-361): 6.56e-09: 61.5: 12.41		PAX6_HUMAN (83-460): 3.74e-59: 204: 15.54
+	Mm
		1142779 EWS_MOUSE (103-334): 1.82e-29: 125: 18.03		Q8VD35_MOUSE (201-448): 2.83e-32: 127: 17.65
+	Hs
		988783 KMT2C_HUMAN (17-365): 1.05e-10: 67.3: 9.52		PAX8_HUMAN (83-439): 4.26e-37: 144: 9.43
+	Hs
		973865 KMT2C_HUMAN (17-365): 1.05e-10: 67.3: 9.52		PAX2_HUMAN (83-401): 6.33e-36: 141: 9.47
+	Hs
		988784 ARI1B_HUMAN (89-361): 6.56e-09: 61.5: 12.41		PAX8_HUMAN (83-439): 4.26e-37: 144: 9.43
+	Hs
		973866 ARI1B_HUMAN (89-361): 6.56e-09: 61.5: 12.41		PAX2_HUMAN (83-401): 6.33e-36: 141: 9.47
+	Hs
		822650 KMT2C_HUMAN (17-365): 1.05e-10: 67.3: 9.52		LHX1_HUMAN (151-483): 7.34e-30: 123: 14.58
+	Hs
		822651 ARI1B_HUMAN (89-361): 6.56e-09: 61.5: 12.41		LHX1_HUMAN (151-483): 7.34e-30: 123: 14.58