Protein: RHBT2
Rho-related BTB domain-containing protein 2 (Deleted in breast cancer 2 gene protein) (p83)

Gene: RHBT2, RHOBTB2
Organism: Homo sapiens
Interactions: 164
UniProt ID: Q9BYZ6

Gene Ontology (top 5):
GO:0003924 - GTPase activity
GO:0005525 - GTP binding
GO:0005856 - cytoskeleton
GO:0005886 - plasma membrane
GO:0007015 - actin filament organization

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1114215

CUL3
Cullin-3

5

20

Small-scale

0.931

High

322759

RHBT3
Rho-related BTB domain-containing protein 3

1

20

Small-scale

0.713

High

1419415

RHBT2
Rho-related BTB domain-containing protein 2

1

20

Small-scale

0.713

High

355027

CHK2
Serine/threonine-protein kinase Chk2

1

15

High-throughput

0.698

High

411035

ERBB2
Receptor tyrosine-protein kinase erbB-2

1

20

High-throughput

0.698

High

641252

FGFR2
Fibroblast growth factor receptor 2

1

20

High-throughput

0.698

High

1154438

STK11
Serine/threonine-protein kinase STK11

1

4

High-throughput

0.698

High

1419440

PKP3
Plakophilin-3

1

20

High-throughput

0.691

High

461899

HS90A
Heat shock protein HSP 90-alpha

2

15

Small-scale

0.620

High

1419421

PAK6
Serine/threonine-protein kinase PAK 6

1

20

High-throughput

0.618

High

507042

POTEJ
POTE ankyrin domain family member J

1

15

High-throughput

0.618

High

710466

EPHA2
Ephrin type-A receptor 2

1

20

High-throughput

0.618

High

902045

RAB9A
Ras-related protein Rab-9A

1

20

High-throughput

0.618

High

956472

RAB2A
Ras-related protein Rab-2A

1

20

High-throughput

0.618

High

962445

RHOA
Transforming protein RhoA

1

19

High-throughput

0.618

High

981351

RAB1A
Ras-related protein Rab-1A

1

20

High-throughput

0.618

High

1295549

MIB1
E3 ubiquitin-protein ligase MIB1

1

19

High-throughput

0.618

High

1351386

DLG5
Disks large homolog 5

1

20

High-throughput

0.618

High

1419441

MYO5A
Unconventional myosin-Va

1

20

High-throughput

0.618

High

1094411

CSN1
COP9 signalosome complex subunit 1

3

8

High-throughput

0.593

High

326777

DUS14
Dual specificity protein phosphatase 14

2

6

High-throughput

0.574

High

342408

APBB3
Amyloid-beta A4 precursor protein-binding family B member 3

2

4

High-throughput

0.574

High

1419442

ARI1
E3 ubiquitin-protein ligase ARIH1

2

10

High-throughput

0.574

High

958708

CSN2
COP9 signalosome complex subunit 2

2

14

High-throughput

0.571

High

1371855

CUL5
Cullin-5

1

20

Small-scale

0.555

High

220985

XPOT
Exportin-T

1

11

High-throughput

0.553

High

783655

MP2K2
Dual specificity mitogen-activated protein kinase kinase 2

1

19

High-throughput

0.553

High

934160

XPO2
Exportin-2

1

20

High-throughput

0.553

High

986695

PPIA
Peptidyl-prolyl cis-trans isomerase A

1

10

High-throughput

0.553

High

1109210

PRP4K
Serine/threonine-protein kinase PRP4 homolog

1

20

High-throughput

0.553

High

1144307

STK38
Serine/threonine-protein kinase 38

1

20

High-throughput

0.553

High

1357418

DEP1B
DEP domain-containing protein 1B

1

20

High-throughput

0.553

High

1419430

IPO11
Importin-11

1

17

High-throughput

0.553

High

468768

HS90B
Heat shock protein HSP 90-beta

1

15

Small-scale

0.552

High

336770

BAG4
BAG family molecular chaperone regulator 4

1

3

High-throughput

0.541

High

611327

PTN1
Tyrosine-protein phosphatase non-receptor type 1

1

20

High-throughput

0.541

High

464207

TPM2
Tropomyosin beta chain

1

10

High-throughput

0.536

High

1387467

MSI2H
RNA-binding protein Musashi homolog 2

1

15

Small-scale

0.528

High

1272550

CSN6
COP9 signalosome complex subunit 6

2

3

High-throughput

0.521

High

186224

PPM1D
Protein phosphatase 1D

1

2

High-throughput

0.494

High

123820

MYO1C
Unconventional myosin-Ic

1

20

High-throughput

0.479

High

270399

WDR1
WD repeat-containing protein 1

1

16

High-throughput

0.479

High

277812

H2AY
Core histone macro-H2A.1

1

10

High-throughput

0.479

High

299358

FLOT1
Flotillin-1

1

20

High-throughput

0.479

High

447853

TPM3
Tropomyosin alpha-3 chain

1

11

High-throughput

0.479

High

482961

TPM1
Tropomyosin alpha-1 chain

1

18

High-throughput

0.479

High

538675

GTR1
Solute carrier family 2, facilitated glucose transporter member 1

1

20

High-throughput

0.479

High

555751

ACTN1
Alpha-actinin-1

1

17

High-throughput

0.479

High

697646

PYR1
Multifunctional protein CAD

1

6

High-throughput

0.479

High

842853

CDN2A
Cyclin-dependent kinase inhibitor 2A

1

20

High-throughput

0.479

High

867398

CAPZB
F-actin-capping protein subunit beta

1

5

High-throughput

0.479

High

930362

AAKG1
5'-AMP-activated protein kinase subunit gamma-1

1

4

High-throughput

0.479

High

993319

ACTG
Actin, cytoplasmic 2

1

14

High-throughput

0.479

High

995472

TPM4
Tropomyosin alpha-4 chain

1

14

High-throughput

0.479

High

1026208

CLH1
Clathrin heavy chain 1

1

12

High-throughput

0.479

High

1140804

KIF14
Kinesin-like protein KIF14

1

20

High-throughput

0.479

High

1158522

CDC37
Hsp90 co-chaperone Cdc37

1

1

Small-scale

0.479

High

1160748

DREB
Drebrin

1

20

High-throughput

0.479

High

1258305

MOB2
MOB kinase activator 2

1

2

High-throughput

0.479

High

1359696

PHIP
PH-interacting protein

1

18

High-throughput

0.479

High

1419425

TMOD3
Tropomodulin-3

1

12

High-throughput

0.479

High

1419432

MYO6
Unconventional myosin-VI

1

20

High-throughput

0.479

High

948467

ARPC4
Actin-related protein 2/3 complex subunit 4

1

0

High-throughput

0.458

High

1419433

CSN3
COP9 signalosome complex subunit 3

1

14

High-throughput

0.445

High

128313

PSD12
26S proteasome non-ATPase regulatory subunit 12

1

10

High-throughput

0.437

High

215345

TXNL1
Thioredoxin-like protein 1

1

8

High-throughput

0.437

High

245152

AQR
RNA helicase aquarius

1

6

High-throughput

0.437

High

248619

FADS1
Acyl-CoA

1

11

High-throughput

0.437

High

251035

PRP17
Pre-mRNA-processing factor 17

1

8

High-throughput

0.437

High

301196

RL1D1
Ribosomal L1 domain-containing protein 1

1

9

High-throughput

0.437

High

348712

AIFM1
Apoptosis-inducing factor 1, mitochondrial

1

5

High-throughput

0.437

High

359871

DYR
Dihydrofolate reductase

1

1

High-throughput

0.437

High

360471

COX2
Cytochrome c oxidase subunit 2

1

2

High-throughput

0.437

High

451263

NFL
Neurofilament light polypeptide

1

15

High-throughput

0.437

High

462617

HNRPC
Heterogeneous nuclear ribonucleoproteins C1/C2

1

14

High-throughput

0.437

High

467955

PFKAM
ATP-dependent 6-phosphofructokinase, muscle type

1

9

High-throughput

0.437

High

502116

H2AZ
Histone H2A.Z

1

8

High-throughput

0.437

High

542199

TOP1
DNA topoisomerase 1

1

5

High-throughput

0.437

High

573989

MYL6B
Myosin light chain 6B

1

16

High-throughput

0.437

High

673951

RS12
Small ribosomal subunit protein eS12

1

2

High-throughput

0.437

High

699082

CALX
Calnexin

1

9

High-throughput

0.437

High

702685

NDUS1
NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial

1

6

High-throughput

0.437

High

717980

2AAA
Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform

1

11

High-throughput

0.437

High

786241

LONM
Lon protease homolog, mitochondrial

1

20

High-throughput

0.437

High

794614

RBMX
RNA-binding motif protein, X chromosome

1

14

High-throughput

0.437

High

821555

TCPZ
T-complex protein 1 subunit zeta

1

2

High-throughput

0.437

High

841245

CNDD3
Condensin-2 complex subunit D3

1

5

High-throughput

0.437

High

863545

STT3A
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A

1

13

High-throughput

0.437

High

884225

SRP09
Signal recognition particle 9 kDa protein

1

7

High-throughput

0.437

High

916338

TXTP
Tricarboxylate transport protein, mitochondrial

1

17

High-throughput

0.437

High

943309

RBM11
Splicing regulator RBM11

1

8

High-throughput

0.437

High

976774

ERF1
Eukaryotic peptide chain release factor subunit 1

1

5

High-throughput

0.437

High

983201

RS26
Small ribosomal subunit protein eS26

1

1

High-throughput

0.437

High

988203

TRA2B
Transformer-2 protein homolog beta

1

18

High-throughput

0.437

High

992072

RL38
Large ribosomal subunit protein eL38

1

4

High-throughput

0.437

High

1007258

TCPB
T-complex protein 1 subunit beta

1

5

High-throughput

0.437

High

1029548

SRSF2
Serine/arginine-rich splicing factor 2

1

6

High-throughput

0.437

High

1032537

PFKAP
ATP-dependent 6-phosphofructokinase, platelet type

1

9

High-throughput

0.437

High

1039565

TOP2B
DNA topoisomerase 2-beta

1

9

High-throughput

0.437

High

1065412

SSRP1
FACT complex subunit SSRP1

1

15

High-throughput

0.437

High

1066770

NCBP1
Nuclear cap-binding protein subunit 1

1

2

High-throughput

0.437

High

1085706

TBL3
Transducin beta-like protein 3

1

15

High-throughput

0.437

High

1085918

TWF1
Twinfilin-1

1

5

High-throughput

0.437

High

1089850

ILF3
Interleukin enhancer-binding factor 3

1

11

High-throughput

0.437

High

1099771

MD2L1
Mitotic spindle assembly checkpoint protein MAD2A

1

1

High-throughput

0.437

High

1118153

DX39B
Spliceosome RNA helicase DDX39B

1

11

High-throughput

0.437

High

1128278

MCM6
DNA replication licensing factor MCM6

1

7

High-throughput

0.437

High

1130435

RRP1B
Ribosomal RNA processing protein 1 homolog B

1

13

High-throughput

0.437

High

1131376

GANAB
Neutral alpha-glucosidase AB

1

5

High-throughput

0.437

High

1140016

RRS1
Ribosome biogenesis regulatory protein homolog

1

2

High-throughput

0.437

High

1143974

IPYR
Inorganic pyrophosphatase

1

8

High-throughput

0.437

High

1153588

MLF2
Myeloid leukemia factor 2

1

2

High-throughput

0.437

High

1154923

NEDD8
Ubiquitin-like protein NEDD8

1

11

High-throughput

0.437

High

1160572

SMN
Survival motor neuron protein

1

4

High-throughput

0.437

High

1168884

HNRL2
Heterogeneous nuclear ribonucleoprotein U-like protein 2

1

14

High-throughput

0.437

High

1211793

SYRM
Probable arginine--tRNA ligase, mitochondrial

1

4

High-throughput

0.437

High

1256403

TPGS1
Tubulin polyglutamylase complex subunit 1

1

1

High-throughput

0.437

High

1271131

TM10C
tRNA methyltransferase 10 homolog C

1

5

High-throughput

0.437

High

1310725

PHF6
PHD finger protein 6

1

4

High-throughput

0.437

High

1314149

RAVR1
Ribonucleoprotein PTB-binding 1

1

11

High-throughput

0.437

High

1314689

SRRM1
Serine/arginine repetitive matrix protein 1

1

20

High-throughput

0.437

High

1351466

BRX1
Ribosome biogenesis protein BRX1 homolog

1

6

High-throughput

0.437

High

1359911

PRP31
U4/U6 small nuclear ribonucleoprotein Prp31

1

4

High-throughput

0.437

High

1365901

NU205
Nuclear pore complex protein Nup205

1

7

High-throughput

0.437

High

1370094

RENT1
Regulator of nonsense transcripts 1

1

5

High-throughput

0.437

High

1370351

CSN5
COP9 signalosome complex subunit 5

1

8

High-throughput

0.437

High

1371522

USP9X
Ubiquitin carboxyl-terminal hydrolase 9X

1

13

High-throughput

0.437

High

1380959

LMBL2
Lethal(3)malignant brain tumor-like protein 2

1

3

High-throughput

0.437

High

1381342

NCLN
BOS complex subunit NCLN

1

8

High-throughput

0.437

High

1403567

MMS19
MMS19 nucleotide excision repair protein homolog

1

3

High-throughput

0.437

High

1404572

PSMD1
26S proteasome non-ATPase regulatory subunit 1

1

5

High-throughput

0.437

High

1407556

TCPH
T-complex protein 1 subunit eta

1

1

High-throughput

0.437

High

1410124

GRWD1
Glutamate-rich WD repeat-containing protein 1

1

15

High-throughput

0.437

High

1413193

CSN4
COP9 signalosome complex subunit 4

1

5

High-throughput

0.437

High

1413292

WAC
WW domain-containing adapter protein with coiled-coil

1

11

High-throughput

0.437

High

1419416

CRNL1
Crooked neck-like protein 1

1

12

High-throughput

0.437

High

1419418

SDS3
Sin3 histone deacetylase corepressor complex component SDS3

1

3

High-throughput

0.437

High

1419419

CYBP
Calcyclin-binding protein

1

4

High-throughput

0.437

High

1419422

SYFB
Phenylalanine--tRNA ligase beta subunit

1

3

High-throughput

0.437

High

1419423

MDN1
Midasin

1

16

High-throughput

0.437

High

1419424

DDX56
Probable ATP-dependent RNA helicase DDX56

1

20

High-throughput

0.437

High

1419426

CEP72
Centrosomal protein of 72 kDa

1

20

High-throughput

0.437

High

1419427

DHCR7
7-dehydrocholesterol reductase

1

15

High-throughput

0.437

High

1419428

CSN7A
COP9 signalosome complex subunit 7a

1

5

High-throughput

0.437

High

1419429

KDM5B
Lysine-specific demethylase 5B

1

6

Small-scale

0.437

High

1419431

RALY
RNA-binding protein Raly

1

7

High-throughput

0.437

High

1419434

NSF1C
NSFL1 cofactor p47

1

4

High-throughput

0.437

High

1419435

CP131
Centrosomal protein of 131 kDa

1

20

High-throughput

0.437

High

1419436

COF2
Cofilin-2

1

5

High-throughput

0.437

High

1419437

ADIP
Afadin- and alpha-actinin-binding protein

1

3

High-throughput

0.437

High

1419438

MTO1
5-taurinomethyluridine-[tRNA] synthase subunit MTO1, mitochondrial

1

2

High-throughput

0.437

High

1419439

RL36
Large ribosomal subunit protein eL36

1

2

High-throughput

0.437

High

1419443

SP16H
FACT complex subunit SPT16

1

5

High-throughput

0.437

High

1419444

RBM8A
RNA-binding protein 8A

1

13

High-throughput

0.437

High

1419445

LRRF2
Leucine-rich repeat flightless-interacting protein 2

1

20

High-throughput

0.437

High

1294955

PALB2
Partner and localizer of BRCA2

1

0

High-throughput

0.282

High

751339

DUT
Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial

1

0

High-throughput

0.249

Low

941258

IF6
Eukaryotic translation initiation factor 6

1

0

High-throughput

0.249

Low

1157911

DDB1
DNA damage-binding protein 1

1

0

High-throughput

0.249

Low

1409655

CND3
Condensin complex subunit 3

1

0

High-throughput

0.249

Low

1413462

MCMBP
Mini-chromosome maintenance complex-binding protein

1

0

High-throughput

0.249

Low

1419417

RPF2
Ribosome production factor 2 homolog

1

0

High-throughput

0.249

Low

1419420

Q9HCK3
KIAA1569 protein

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025