HitPredict

Interactor 1: RAB3D (O95716)
Ras-related protein Rab-3D
Gene: RAB3D

Interactor 2: MSS4 (P47224)
Guanine nucleotide exchange factor MSS4 (Rab-interacting factor)
Gene: RABIF

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.61	0.80	0.700

Property	Details
Experiments	32296183, unassigned1304
Identification Methods	two hybrid, two hybrid prey pooling approach, two hybrid array, validated two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	Mss4~Ras
Common GO terms	-
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 219 Hs			1 123
+	Hs
		812751 RAB8B_HUMAN (17-212): 8.22e-100: 289: 47.96		MSS4_HUMAN (1-123): 1.15e-71: 211: 100.00
+	Hs
		812737 RAB1A_HUMAN (13-219): 1.28e-90: 266: 43.96		MSS4_HUMAN (1-123): 1.15e-71: 211: 100.00
+	Mm
		918998 RAB1A_MOUSE (13-219): 1.28e-90: 266: 43.96		MSS4_MOUSE (1-123): 1.15e-71: 211: 93.50
+	Hs
		812757 RAB1B_HUMAN (15-219): 2.43e-88: 260: 43.90		MSS4_HUMAN (1-123): 1.15e-71: 211: 100.00
+	Hs
		591458 RAB3A_HUMAN (1-219): 9.08e-88: 259: 76.82		MSS4_HUMAN (1-123): 1.15e-71: 211: 100.00
+	Hs
		591520 RAB3B_HUMAN (1-219): 1.47e-87: 259: 75.80		MSS4_HUMAN (1-123): 1.15e-71: 211: 100.00
+	Hs
		812735 RAB8A_HUMAN (15-214): 5.52e-87: 257: 50.00		MSS4_HUMAN (1-123): 1.15e-71: 211: 100.00
+	Hs
		812752 RAB3C_HUMAN (1-219): 1.3e-84: 252: 73.52		MSS4_HUMAN (1-123): 1.15e-71: 211: 100.00
+	Dm
		627448 RAB3_DROME (1-219): 5.13e-89: 262: 74.21		MSS4_DROME (13-123): 3.14e-52: 162: 39.29
+	Dm
		185502 O18332_DROME (13-218): 1.26e-85: 254: 41.75		MSS4_DROME (13-123): 3.14e-52: 162: 39.29
+	Hs
		812736 RAB10_HUMAN (15-201): 2.57e-66: 204: 50.26		MSS4_HUMAN (1-123): 1.15e-71: 211: 100.00
+	Dm
		183445 O15971_DROME (15-186): 2.84e-64: 199: 52.91		MSS4_DROME (13-123): 3.14e-52: 162: 39.29
+	Dm
		185729 O18338_DROME (17-195): 1.84e-62: 195: 50.28		MSS4_DROME (13-123): 3.14e-52: 162: 39.29