Protein: DX39A
ATP-dependent RNA helicase DDX39A (EC 3.6.4.13) (DEAD box protein 39) (Nuclear RNA helicase URH49)

Gene: DX39A, DDX39A
Organism: Homo sapiens
Interactions: 177
UniProt ID: O00148

Gene Ontology (top 5):
GO:0000398 - mRNA splicing, via spliceosome
GO:0003723 - RNA binding
GO:0003724 - RNA helicase activity
GO:0003729 - mRNA binding
GO:0005524 - ATP binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

117138

DX39B
Spliceosome RNA helicase DDX39B

6

18

Small-scale

0.940

High

117057

DX39A
ATP-dependent RNA helicase DDX39A

3

17

High-throughput

0.861

High

117123

SARNP
SAP domain-containing ribonucleoprotein

7

3

Small-scale

0.755

High

117185

THOC2
THO complex subunit 2

1

13

High-throughput

0.691

High

117229

CHTOP
Chromatin target of PRMT1 protein

4

2

High-throughput

0.689

High

117147

TERF2
Telomeric repeat-binding factor 2

3

1

High-throughput

0.669

High

117153

NCBP3
Nuclear cap-binding protein subunit 3

3

3

High-throughput

0.650

High

117199

THOC1
THO complex subunit 1

2

3

High-throughput

0.628

High

117103

RECQ1
ATP-dependent DNA helicase Q1

1

19

High-throughput

0.618

High

117127

CHD3
Chromodomain-helicase-DNA-binding protein 3

1

10

High-throughput

0.618

High

117142

CHD4
Chromodomain-helicase-DNA-binding protein 4

1

10

High-throughput

0.618

High

117169

TRI67
Tripartite motif-containing protein 67

1

13

High-throughput

0.618

High

117228

HECD1
E3 ubiquitin-protein ligase HECTD1

1

15

High-throughput

0.618

High

117104

SOX2
Transcription factor SOX-2

2

13

High-throughput

0.611

High

117120

TBA4A
Tubulin alpha-4A chain

2

5

High-throughput

0.611

High

117218

CELR2
Cadherin EGF LAG seven-pass G-type receptor 2

2

3

High-throughput

0.611

High

117121

RNF4
E3 ubiquitin-protein ligase RNF4

2

3

High-throughput

0.606

High

117174

THOC4
THO complex subunit 4

2

20

Small-scale

0.595

High

117064

PRKN
E3 ubiquitin-protein ligase parkin

2

15

High-throughput

0.584

High

117136

CUL4A
Cullin-4A

2

18

High-throughput

0.584

High

117194

FBXW7
F-box/WD repeat-containing protein 7

2

12

Small-scale

0.584

High

117119

UBC9
SUMO-conjugating enzyme UBC9

2

10

High-throughput

0.584

High

117093

NFKB1
Nuclear factor NF-kappa-B p105 subunit

1

6

High-throughput

0.575

High

117101

IF4A3
Eukaryotic initiation factor 4A-III

1

19

High-throughput

0.575

High

117225

DDX41
Probable ATP-dependent RNA helicase DDX41

1

19

High-throughput

0.575

High

117155

FGD3
FYVE, RhoGEF and PH domain-containing protein 3

2

5

High-throughput

0.571

High

117193

ESR2
Estrogen receptor beta

2

14

High-throughput

0.571

High

117111

TERF1
Telomeric repeat-binding factor 1

1

1

High-throughput

0.568

High

117167

FAT4
Protocadherin Fat 4

2

3

High-throughput

0.558

High

117188

FAT3
Protocadherin Fat 3

2

5

High-throughput

0.558

High

117181

PLD6
Mitochondrial cardiolipin hydrolase

1

1

High-throughput

0.553

High

117058

FOXE1
Forkhead box protein E1

1

10

High-throughput

0.536

High

117061

AIM2
Interferon-inducible protein AIM2

1

3

High-throughput

0.536

High

117062

FOXS1
Forkhead box protein S1

1

11

High-throughput

0.536

High

117069

FOXH1
Forkhead box protein H1

1

13

High-throughput

0.536

High

117083

SNRPA
U1 small nuclear ribonucleoprotein A

1

20

High-throughput

0.536

High

117084

RU1C
U1 small nuclear ribonucleoprotein C

1

4

High-throughput

0.536

High

117087

TOP1
DNA topoisomerase 1

1

8

High-throughput

0.536

High

117088

RSMB
Small nuclear ribonucleoprotein-associated proteins B and B'

1

4

High-throughput

0.536

High

117113

FOXG1
Forkhead box protein G1

1

12

High-throughput

0.536

High

117114

FOXA3
Hepatocyte nuclear factor 3-gamma

1

10

High-throughput

0.536

High

117115

FOXL2
Forkhead box protein L2

1

11

High-throughput

0.536

High

117122

SRPK2
SRSF protein kinase 2

1

16

High-throughput

0.536

High

117125

SSRP1
FACT complex subunit SSRP1

1

15

High-throughput

0.536

High

117128

FOXC1
Forkhead box protein C1

1

12

High-throughput

0.536

High

117129

FOXI1
Forkhead box protein I1

1

10

High-throughput

0.536

High

117130

FOXL1
Forkhead box protein L1

1

10

High-throughput

0.536

High

117133

TBB3
Tubulin beta-3 chain

1

4

High-throughput

0.536

High

117134

SNW1
SNW domain-containing protein 1

1

5

High-throughput

0.536

High

117137

THOC5
THO complex subunit 5 homolog

1

3

High-throughput

0.536

High

117144

FL2D
Pre-mRNA-splicing regulator WTAP

1

2

High-throughput

0.536

High

117146

SF3A1
Splicing factor 3A subunit 1

1

6

High-throughput

0.536

High

117150

CPSF6
Cleavage and polyadenylation specificity factor subunit 6

1

16

High-throughput

0.536

High

117163

THOC7
THO complex subunit 7 homolog

1

4

High-throughput

0.536

High

117165

ZC3HE
Zinc finger CCCH domain-containing protein 14

1

5

High-throughput

0.536

High

117168

FOXI2
Forkhead box protein I2

1

9

High-throughput

0.536

High

117173

MTA70
N6-adenosine-methyltransferase catalytic subunit

1

5

High-throughput

0.536

High

117175

FOXP4
Forkhead box protein P4

1

10

High-throughput

0.536

High

117176

HSC20
Iron-sulfur cluster co-chaperone protein HscB

1

3

High-throughput

0.536

High

117198

RBM33
RNA-binding protein 33

1

12

High-throughput

0.536

High

117204

CDC5L
Cell division cycle 5-like protein

1

8

High-throughput

0.536

High

117206

FOXB1
Forkhead box protein B1

1

12

High-throughput

0.536

High

117212

FOXQ1
Forkhead box protein Q1

1

12

High-throughput

0.536

High

117226

AGO2
Protein argonaute-2

1

16

High-throughput

0.536

High

117227

AGO1
Protein argonaute-1

1

16

High-throughput

0.536

High

117063

PCDH7
Protocadherin-7

2

5

High-throughput

0.533

High

117221

TE2IP
Telomeric repeat-binding factor 2-interacting protein 1

1

0

High-throughput

0.518

High

117060

SOCS2
Suppressor of cytokine signaling 2

1

5

High-throughput

0.515

High

108880

H0YHG0
DnaJ homolog subfamily C member 14

1

5

High-throughput

0.515

High

117080

HSPB1
Heat shock protein beta-1

1

3

High-throughput

0.515

High

117102

HD
Huntingtin

1

2

High-throughput

0.515

High

117171

Q7KZS0
SUMO-conjugating enzyme UBC9

1

10

High-throughput

0.515

High

117148

TEAD2
Transcriptional enhancer factor TEF-4

1

0

High-throughput

0.513

High

117124

FAK1
Focal adhesion kinase 1

1

5

High-throughput

0.508

High

117116

SUMO2
Small ubiquitin-related modifier 2

1

7

High-throughput

0.501

High

117220

BABA1
BRISC and BRCA1-A complex member 1

1

0

High-throughput

0.493

High

117190

HNRLL
Heterogeneous nuclear ribonucleoprotein L-like

1

18

High-throughput

0.481

High

117059

PSDE
26S proteasome non-ATPase regulatory subunit 14

1

12

High-throughput

0.479

High

117065

GANP
Germinal-center associated nuclear protein

1

4

High-throughput

0.479

High

117066

NUPR1
Nuclear protein 1

1

7

High-throughput

0.479

High

117068

EED
Polycomb protein EED

1

20

High-throughput

0.479

High

117071

UFL1
E3 UFM1-protein ligase 1

1

4

High-throughput

0.479

High

117072

ZBT7A
Zinc finger and BTB domain-containing protein 7A

1

7

Small-scale

0.479

High

117073

HERC2
E3 ubiquitin-protein ligase HERC2

1

13

High-throughput

0.479

High

117074

SNAI1
Zinc finger protein SNAI1

1

5

High-throughput

0.479

High

117076

MYC
Myc proto-oncogene protein

1

12

High-throughput

0.479

High

117078

MYCN
N-myc proto-oncogene protein

1

12

High-throughput

0.479

High

117079

NTRK1
High affinity nerve growth factor receptor

1

8

High-throughput

0.479

High

117081

ISG15
Ubiquitin-like protein ISG15

1

9

High-throughput

0.479

High

117085

PARP1
Poly [ADP-ribose] polymerase 1

1

5

Small-scale

0.479

High

117086

HSP7C
Heat shock cognate 71 kDa protein

1

5

High-throughput

0.479

High

117089

UCHL3
Ubiquitin carboxyl-terminal hydrolase isozyme L3

1

7

Small-scale

0.479

High

117090

VAV
Proto-oncogene vav

1

10

High-throughput

0.479

High

117091

RFA2
Replication protein A 32 kDa subunit

1

8

High-throughput

0.479

High

117092

CEBPB
CCAAT/enhancer-binding protein beta

1

12

High-throughput

0.479

High

117095

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

6

High-throughput

0.479

High

117096

UFO
Tyrosine-protein kinase receptor UFO

1

3

High-throughput

0.479

High

117097

PHB1
Prohibitin 1

1

6

High-throughput

0.479

High

117098

RFA3
Replication protein A 14 kDa subunit

1

6

High-throughput

0.479

High

117099

VGFR3
Vascular endothelial growth factor receptor 3

1

1

High-throughput

0.479

High

117100

BRCA1
Breast cancer type 1 susceptibility protein

1

14

High-throughput

0.479

High

117105

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

10

High-throughput

0.479

High

117107

RBP2
E3 SUMO-protein ligase RanBP2

1

7

Small-scale

0.479

High

117108

CDK9
Cyclin-dependent kinase 9

1

10

High-throughput

0.479

High

117109

UBP11
Ubiquitin carboxyl-terminal hydrolase 11

1

6

High-throughput

0.479

High

117110

ATX3
Ataxin-3

1

1

Small-scale

0.479

High

117112

UBP14
Ubiquitin carboxyl-terminal hydrolase 14

1

6

High-throughput

0.479

High

117117

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

9

High-throughput

0.479

High

117118

RBX1
E3 ubiquitin-protein ligase RBX1

1

1

High-throughput

0.479

High

117126

MN1
Transcriptional activator MN1

1

1

Small-scale

0.479

High

117131

NFX1
Transcriptional repressor NF-X1

1

6

High-throughput

0.479

High

117132

TIF1B
Transcription intermediary factor 1-beta

1

13

High-throughput

0.479

High

117135

CUL3
Cullin-3

1

18

High-throughput

0.479

High

117140

RBM39
RNA-binding protein 39

1

18

High-throughput

0.479

High

117143

RHG19
Rho GTPase-activating protein 19

1

3

High-throughput

0.479

High

117145

TNIP1
TNFAIP3-interacting protein 1

1

20

High-throughput

0.479

High

117149

EZH2
Histone-lysine N-methyltransferase EZH2

1

5

High-throughput

0.479

High

117151

HIF1A
Hypoxia-inducible factor 1-alpha

1

2

High-throughput

0.479

High

117152

IF16
Gamma-interferon-inducible protein 16

1

3

High-throughput

0.479

High

117154

PKHG4
Puratrophin-1

1

5

High-throughput

0.479

High

117159

ARM12
Armadillo repeat-containing protein 12

1

1

Small-scale

0.479

High

117162

VIR
Protein virilizer homolog

1

2

High-throughput

0.479

High

117170

TBA1A
Tubulin alpha-1A chain

1

5

High-throughput

0.479

High

117172

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

3

High-throughput

0.479

High

117177

Z3H7A
Zinc finger CCCH domain-containing protein 7A

1

7

High-throughput

0.479

High

117178

CUL9
Cullin-9

1

11

Small-scale

0.479

High

117183

ZBT38
Zinc finger and BTB domain-containing protein 38

1

1

Small-scale

0.479

High

117184

WDR19
WD repeat-containing protein 19

1

14

High-throughput

0.479

High

117189

DOT1L
Histone-lysine N-methyltransferase, H3 lysine-79 specific

1

2

High-throughput

0.479

High

117191

NALP7
NACHT, LRR and PYD domains-containing protein 7

1

3

High-throughput

0.479

High

117192

DYRK2
Dual specificity tyrosine-phosphorylation-regulated kinase 2

1

15

High-throughput

0.479

High

117195

DCPS
m7GpppX diphosphatase

1

1

High-throughput

0.479

High

117196

OPTN
Optineurin

1

14

High-throughput

0.479

High

117200

DDRGK
DDRGK domain-containing protein 1

1

5

High-throughput

0.479

High

117203

CIC
Protein capicua homolog

1

15

High-throughput

0.479

High

117205

NECD
Necdin

1

6

High-throughput

0.479

High

117207

BAG1
BAG family molecular chaperone regulator 1

1

4

High-throughput

0.479

High

117209

OVOL2
Transcription factor Ovo-like 2

1

4

Small-scale

0.479

High

117210

FACD2
Fanconi anemia group D2 protein

1

9

High-throughput

0.479

High

117211

API5
Apoptosis inhibitor 5

1

3

High-throughput

0.479

High

117213

UBA5
Ubiquitin-like modifier-activating enzyme 5

1

2

High-throughput

0.479

High

117214

SPRTN
DNA-dependent metalloprotease SPRTN

1

3

High-throughput

0.479

High

117216

PKHA4
Pleckstrin homology domain-containing family A member 4

1

12

High-throughput

0.479

High

117217

SMUF1
E3 ubiquitin-protein ligase SMURF1

1

11

High-throughput

0.479

High

117219

FBX6
F-box only protein 6

1

5

High-throughput

0.479

High

117222

CELR1
Cadherin EGF LAG seven-pass G-type receptor 1

1

3

High-throughput

0.479

High

117223

ZRAN1
Ubiquitin thioesterase ZRANB1

1

7

High-throughput

0.479

High

117224

UBQL2
Ubiquilin-2

1

4

High-throughput

0.479

High

117230

TRRAP
Transformation/transcription domain-associated protein

1

6

High-throughput

0.479

High

117179

BBS7
Bardet-Biedl syndrome 7 protein

1

0

High-throughput

0.458

High

117201

MAEL
Protein maelstrom homolog

1

0

Small-scale

0.458

High

117215

TOLIP
Toll-interacting protein

1

0

High-throughput

0.458

High

117077

ANGI
Angiogenin

1

1

High-throughput

0.445

High

117082

JUN
Transcription factor Jun

1

13

High-throughput

0.445

High

117141

RRP1B
Ribosomal RNA processing protein 1 homolog B

1

5

High-throughput

0.445

High

117156

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

8

High-throughput

0.445

High

117180

SLX4
Structure-specific endonuclease subunit SLX4

1

8

High-throughput

0.445

High

117182

RYBP
RING1 and YY1-binding protein

1

5

High-throughput

0.445

High

117075

AGR2
Anterior gradient protein 2 homolog

1

4

High-throughput

0.437

High

117139

GRM2
Metabotropic glutamate receptor 2

1

1

High-throughput

0.437

High

117157

FREM2
FRAS1-related extracellular matrix protein 2

1

4

High-throughput

0.437

High

117160

OTUD1
OTU domain-containing protein 1

1

3

High-throughput

0.437

High

117161

A16L1
Autophagy-related protein 16-1

1

15

High-throughput

0.437

High

117164

FBX42
F-box only protein 42

1

4

High-throughput

0.437

High

117186

DPTOR
DEP domain-containing mTOR-interacting protein

1

1

Small-scale

0.437

High

117202

SNX27
Sorting nexin-27

1

3

High-throughput

0.437

High

117166

TMIG1
Transmembrane and immunoglobulin domain-containing protein 1

1

0

Small-scale

0.426

High

117106

CEBPA
CCAAT/enhancer-binding protein alpha

1

12

High-throughput

0.408

High

136

A0A024R6X4
PLEKHG4

1

5

High-throughput

0.407

High

117197

Q96D37
VAV1 protein

1

10

High-throughput

0.407

High

117208

TM2D3
TM2 domain-containing protein 3

2

0

High-throughput

0.318

High

117094

SAT1
Diamine acetyltransferase 1

1

0

High-throughput

0.299

High

117158

CSCL2
CSC1-like protein 2

1

0

High-throughput

0.279

Low

117187

PHOP1
Phosphoethanolamine/phosphocholine phosphatase

1

0

High-throughput

0.279

Low

117070

WFS1
Wolframin

1

0

High-throughput

0.268

Low

117067

NIPS2
Protein NipSnap homolog 2

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024