HitPredict

Interactor 1: HS74L (O95757)
Heat shock 70 kDa protein 4L (Heat shock 70-related protein APG-1) (Heat shock protein family H member 3) (Heat-shock protein family A member 4-like protein) (HSPA4-like protein) (Osmotic stress protein 94)
Gene: HSPA4L

Interactor 2: SYUA (P37840)
Alpha-synuclein (Non-A beta component of AD amyloid) (Non-A4 component of amyloid precursor) (NACP)
Gene: SNCA

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.66	0.60	0.633

Property	Details
Experiments	31980649, 36634849, unassigned2173
Identification Methods	affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 839 Hs			1 140
+	Rn
		291982 HSP74_RAT (1-839): 0: 934: 61.89		SYUA_RAT (1-140): 2.23e-57: 176: 95.00
+	Hs
		714118 HSP74_HUMAN (1-839): 0: 931: 62.60		SYUA_HUMAN (1-140): 5.01e-57: 175: 100.00
+	Hs
		742439 HS105_HUMAN (1-839): 0: 925: 58.24		SYUA_HUMAN (1-140): 5.01e-57: 175: 100.00
+	Hs
		503576 HSP7C_HUMAN (563-695): 1.3e-27: 121: 17.91		SYUA_HUMAN (1-140): 5.01e-57: 175: 100.00
+	Hs
		713917 HS71L_HUMAN (563-703): 9.9e-28: 121: 19.72		SYUA_HUMAN (1-140): 5.01e-57: 175: 100.00
+	Rn
		741578 HSP7C_RAT (563-695): 2.64e-27: 120: 17.16		SYUA_RAT (1-140): 2.23e-57: 176: 95.00