HitPredict

Interactor 1: STAU1 (O95793)
Double-stranded RNA-binding protein Staufen homolog 1
Gene: STAU1

Interactor 2: IF2B1 (Q9NZI8)
Insulin-like growth factor 2 mRNA-binding protein 1 (IGF2 mRNA-binding protein 1) (IMP-1) (IMP1) (Coding region determinant-binding protein) (CRD-BP) (IGF-II mRNA-binding protein 1) (VICKZ family member 1) (Zipcode-binding protein 1) (ZBP-1)
Gene: IGF2BP1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.72	0.60	0.660

Property	Details
Experiments	35271311, 23125841, 19029303
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0003729 - mRNA binding GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0010494 - cytoplasmic stress granule and 1 others more... GO:0043025 - neuronal cell body
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 577 Hs			1 577
+	Hs
		127970 STAU1_HUMAN (1-577): 0: 524: 100.00		IF2B3_HUMAN (1-577): 4.61e-149: 443: 71.85
+	Mm
		291676 STAU1_MOUSE (89-577): 5.34e-156: 457: 91.00		IF2B1_MOUSE (1-577): 3.04e-147: 438: 99.31
+	Hs
		322667 STAU1_HUMAN (1-577): 0: 524: 100.00		PCBP2_HUMAN (407-575): 6.35e-44: 162: 27.43
+	Hs
		1302237 STRBP_HUMAN (48-336): 1.3e-63: 223: 17.33		IF2B1_HUMAN (1-577): 4.69e-147: 437: 100.00
+	Hs
		323382 STAU1_HUMAN (1-577): 0: 524: 100.00		IF2B2_HUMAN (79-477): 2.19e-19: 93.9: 14.84
+	Hs
		323003 STAU1_HUMAN (1-577): 0: 524: 100.00		FUBP3_HUMAN (190-413): 5.36e-18: 89.3: 18.25
+	Hs
		322977 STAU1_HUMAN (1-577): 0: 524: 100.00		FUBP1_HUMAN (118-353): 1.13e-15: 82.3: 14.01
+	Hs
		322959 STAU1_HUMAN (1-577): 0: 524: 100.00		FUBP2_HUMAN (118-416): 2.4e-14: 78.1: 15.89
+	Hs
		322666 STAU1_HUMAN (1-577): 0: 524: 100.00		PCBP1_HUMAN (476-574): 1.53e-12: 71: 17.17
+	Hs
		322391 STAU1_HUMAN (1-577): 0: 524: 100.00		PCBP3_HUMAN (65-270): 1.9e-09: 61.5: 15.31
+	Hs
		269921 PRKRA_HUMAN (67-353): 1.54e-30: 123: 19.42		IF2B1_HUMAN (1-577): 4.69e-147: 437: 100.00
+	Hs
		1346003 STAU2_HUMAN (177-569): 4.96e-21: 99: 16.46		IF2B1_HUMAN (1-577): 4.69e-147: 437: 100.00
+	Hs
		1264623 DGCR8_HUMAN (19-423): 7.12e-36: 145: 15.26		FUBP2_HUMAN (118-416): 2.4e-14: 78.1: 15.89
+	Hs
		944884 RED1_HUMAN (254-488): 1.1e-31: 132: 17.92		FUBP2_HUMAN (118-416): 2.4e-14: 78.1: 15.89
+	Hs
		269828 PRKRA_HUMAN (67-353): 1.54e-30: 123: 19.42		FUBP1_HUMAN (118-353): 1.13e-15: 82.3: 14.01
+	Hs
		944795 RED1_HUMAN (254-488): 1.1e-31: 132: 17.92		PCBP1_HUMAN (476-574): 1.53e-12: 71: 17.17
+	Hs
		269741 PRKRA_HUMAN (67-353): 1.54e-30: 123: 19.42		PCBP1_HUMAN (476-574): 1.53e-12: 71: 17.17
+	Hs
		1346020 STAU2_HUMAN (177-569): 4.96e-21: 99: 16.46		IF2B2_HUMAN (79-477): 2.19e-19: 93.9: 14.84
+	Mm
		956556 TRBP2_MOUSE (87-352): 3.06e-17: 85.5: 17.11		PCBP2_MOUSE (264-489): 7.7e-25: 107: 19.47
+	Hs
		1075620 TRBP2_HUMAN (87-297): 3.18e-16: 82.4: 17.97		FUBP2_HUMAN (118-416): 2.4e-14: 78.1: 15.89