Protein: RFX3
Transcription factor RFX3 (Regulatory factor X 3)

Gene: RFX3
Organism: Homo sapiens
Interactions: 45
UniProt ID: P48380

Gene Ontology (top 5):
GO:0000785 - chromatin
GO:0000976 - transcription cis-regulatory region binding
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0003677 - DNA binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

871780

FHL2
Four and a half LIM domains protein 2

7

3

High-throughput

0.751

High

871792

FOXJ1
Forkhead box protein J1

4

14

High-throughput

0.704

High

651067

RFX1
MHC class II regulatory factor RFX1

3

9

High-throughput

0.662

High

133851

FOXN3
Forkhead box protein N3

2

14

High-throughput

0.628

High

871779

FHL3
Four and a half LIM domains protein 3

2

3

High-throughput

0.628

High

871794

PABP5
Polyadenylate-binding protein 5

2

0

High-throughput

0.585

High

871781

TRIP6
Thyroid receptor-interacting protein 6

1

0

High-throughput

0.549

High

167187

IRF6
Interferon regulatory factor 6

1

1

High-throughput

0.541

High

593051

CREB1
Cyclic AMP-responsive element-binding protein 1

1

2

High-throughput

0.541

High

871776

EWS
RNA-binding protein EWS

1

4

High-throughput

0.541

High

871788

RFX6
DNA-binding protein RFX6

1

9

High-throughput

0.541

High

871751

RFX2
DNA-binding protein RFX2

1

9

High-throughput

0.536

High

871796

INP5K
Inositol polyphosphate 5-phosphatase K

1

1

High-throughput

0.536

High

871801

FOXJ2
Forkhead box protein J2

1

12

High-throughput

0.536

High

138460

BIN1
Myc box-dependent-interacting protein 1

1

0

High-throughput

0.518

High

871774

PKNX1
Homeobox protein PKNOX1

1

0

High-throughput

0.518

High

871784

Q6FHY5
MEOX2 protein

1

1

High-throughput

0.515

High

853923

KI67
Proliferation marker protein Ki-67

1

0

High-throughput

0.513

High

871806

MTCH2
Mitochondrial carrier homolog 2

1

0

High-throughput

0.513

High

871793

IGSF8
Immunoglobulin superfamily member 8

1

1

High-throughput

0.489

High

871772

MEOX2
Homeobox protein MOX-2

1

1

High-throughput

0.481

High

871771

SOX2
Transcription factor SOX-2

1

3

High-throughput

0.479

High

871773

PLK1
Serine/threonine-protein kinase PLK1

1

2

High-throughput

0.479

High

871778

HDAC1
Histone deacetylase 1

1

3

High-throughput

0.479

High

871782

RFX4
Transcription factor RFX4

1

9

Small-scale

0.479

High

871791

HDAC2
Histone deacetylase 2

1

3

High-throughput

0.479

High

871807

TAF6L
TAF6-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 6L

1

1

High-throughput

0.479

High

316779

MTA2
Metastasis-associated protein MTA2

1

0

High-throughput

0.458

High

871787

PTOV1
Prostate tumor-overexpressed gene 1 protein

1

0

High-throughput

0.458

High

871789

CDK20
Cyclin-dependent kinase 20

1

0

High-throughput

0.458

High

871790

DDX1
ATP-dependent RNA helicase DDX1

1

0

High-throughput

0.458

High

871798

ACAD9
Complex I assembly factor ACAD9, mitochondrial

1

0

High-throughput

0.458

High

871802

MBD2
Methyl-CpG-binding domain protein 2

1

0

High-throughput

0.458

High

871804

RTCB
RNA-splicing ligase RtcB homolog

1

0

High-throughput

0.458

High

871805

CFA20
Cilia- and flagella-associated protein 20

1

0

High-throughput

0.458

High

871775

TF2B
Transcription initiation factor IIB

1

1

High-throughput

0.445

High

871785

TRI67
Tripartite motif-containing protein 67

1

2

High-throughput

0.437

High

871797

XYLT2
Xylosyltransferase 2

1

1

High-throughput

0.437

High

871783

C2D1B
Coiled-coil and C2 domain-containing protein 1B

1

0

High-throughput

0.426

High

871777

TRAF2
TNF receptor-associated factor 2

4

0

High-throughput

0.365

High

871786

TMED4
Transmembrane emp24 domain-containing protein 4

1

0

High-throughput

0.279

Low

871799

MINY3
Ubiquitin carboxyl-terminal hydrolase MINDY-3

1

0

High-throughput

0.279

Low

871800

VPS45
Vacuolar protein sorting-associated protein 45

1

0

High-throughput

0.279

Low

871795

BROMI
Protein broad-minded

1

0

High-throughput

0.249

Low

871803

SEC63
Translocation protein SEC63 homolog

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025