HitPredict

Interactor 1: BAG2 (O95816)
BAG family molecular chaperone regulator 2 (BAG-2) (Bcl-2-associated athanogene 2)
Gene: BAG2

Interactor 2: ASPP2 (Q13625)
Apoptosis-stimulating of p53 protein 2 (Bcl2-binding protein) (Bbp) (Renal carcinoma antigen NY-REN-51) (Tumor suppressor p53-binding protein 2) (53BP2) (p53-binding protein 2) (p53BP2)
Gene: TP53BP2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 211 Hs			1 1128
+	Hs
		323969 BAG2_HUMAN (1-211): 3e-99: 288: 100.00		ASPP1_HUMAN (1-1128): 4.45e-135: 439: 45.38
+	Hs
		323924 BAG2_HUMAN (1-211): 3e-99: 288: 100.00		IASPP_HUMAN (416-1127): 1.13e-53: 204: 21.65
+	Hs
		324034 BAG2_HUMAN (1-211): 3e-99: 288: 100.00		Q9H4D1_HUMAN (573-1024): 4.3e-26: 117: 11.58
+	Hs
		323667 BAG2_HUMAN (1-211): 3e-99: 288: 100.00		RIPK4_HUMAN (863-1024): 1.42e-25: 116: 19.63
+	Hs
		323655 BAG2_HUMAN (1-211): 3e-99: 288: 100.00		DAPK1_HUMAN (791-1011): 1.31e-20: 100: 13.12
+	Hs
		323876 BAG2_HUMAN (1-211): 3e-99: 288: 100.00		ANKH1_HUMAN (922-1013): 2.42e-20: 100: 30.44
+	Hs
		161274 BAG2_HUMAN (1-211): 3e-99: 288: 100.00		MYPT1_HUMAN (957-1059): 1.81e-16: 87.2: 36.89