HitPredict

Interactor 1: BAG2 (O95816)
BAG family molecular chaperone regulator 2 (BAG-2) (Bcl-2-associated athanogene 2)
Gene: BAG2

Interactor 2: PINK1 (Q9BXM7)
Serine/threonine-protein kinase PINK1, mitochondrial (EC 2.7.11.1) (BRPK) (PTEN-induced putative kinase protein 1)
Gene: PINK1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.69	0.60	0.646

Property	Details
Experiments	24513209, 24383081
Identification Methods	affinity chromatography technology, pull down
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0030424 - axon GO:0031625 - ubiquitin protein ligase binding GO:0050821 - protein stabilization
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 211 Hs			1 581
+	Hs
		323624 BAG2_HUMAN (1-211): 3e-99: 288: 100.00		KPCI_HUMAN (56-568): 6.26e-123: 376: 13.92
+	Hs
		323609 BAG2_HUMAN (1-211): 3e-99: 288: 100.00		AKT1_HUMAN (115-573): 2.58e-118: 360: 12.89
+	Hs
		323708 BAG2_HUMAN (1-211): 3e-99: 288: 100.00		KPCZ_HUMAN (54-568): 6.17e-114: 353: 13.97
+	Hs
		323575 BAG2_HUMAN (1-211): 3e-99: 288: 100.00		KAPCA_HUMAN (173-567): 1.06e-110: 336: 13.89
+	Hs
		323646 BAG2_HUMAN (1-211): 3e-99: 288: 100.00		KS6A3_HUMAN (154-555): 2.08e-92: 301: 16.59
+	Hs
		324125 BAG2_HUMAN (1-211): 3e-99: 288: 100.00		KCC2A_HUMAN (221-538): 5.11e-82: 266: 20.62