Interactor 1: BAG2 (O95816)
BAG family molecular chaperone regulator 2 (BAG-2) (Bcl-2-associated athanogene 2)
Gene: BAG2

Interactor 2: CHIP (Q9UNE7)
E3 ubiquitin-protein ligase CHIP (EC 2.3.2.27) (Antigen NY-CO-7) (CLL-associated antigen KW-8) (Carboxy terminus of Hsp70-interacting protein) (RING-type E3 ubiquitin transferase CHIP) (STIP1 homology and U box-containing protein 1)
Gene: STUB1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.89 0.60 0.733

The method score is based on:

Property Details
Experiments 33961781, 33987175, 16169850, 16207813, 25036637, 24981860
Identification Methods affinity chromatography technology, pull down, anti tag coimmunoprecipitation, luminescence based mammalian interactome mapping
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005829 - cytosol
GO:0031072 - heat shock protein binding
GO:0031625 - ubiquitin protein ligase binding
GO:0048156 - tau protein binding
GO:0050821 - protein stabilization
and 2 others

more...

Homologous interactions 4

Homologous interactions

Color coding for hit scores

1 211
Hs

1 303
+ Hs
+ Hs
+ Mm
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024