HitPredict

Interactor 1: HEXI1 (O94992)
Protein HEXIM1 (Cardiac lineage protein 1) (Estrogen down-regulated gene 1 protein) (Hexamethylene bis-acetamide-inducible protein 1) (Menage a quatre protein 1)
Gene: HEXIM1

Interactor 2: HMGB1 (P09429)
High mobility group protein B1 (High mobility group protein 1) (HMG-1)
Gene: HMGB1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	29845934
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0002218 - activation of innate immune response GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0045087 - innate immune response
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 359 Hs			1 215
+	Hs
		324556 HEXI1_HUMAN (1-359): 5.54e-159: 451: 100.00		HMGB2_HUMAN (1-187): 7.94e-42: 142: 82.89
+	Hs
		186603 HEXI1_HUMAN (1-359): 5.54e-159: 451: 100.00		HMGB3_HUMAN (13-181): 1.46e-41: 141: 71.60
+	Hs
		324819 HEXI1_HUMAN (1-359): 5.54e-159: 451: 100.00		SSRP1_HUMAN (53-164): 1.6e-28: 114: 37.50
+	Hs
		318427 HEXI1_HUMAN (1-359): 5.54e-159: 451: 100.00		TOX4_HUMAN (91-163): 1.2e-27: 111: 38.36
+	Hs
		324791 HEXI1_HUMAN (1-359): 5.54e-159: 451: 100.00		TFAM_HUMAN (95-186): 2.96e-09: 57.1: 17.39