Protein: TOX4
TOX high mobility group box family member 4

Gene: TOX4
Organism: Homo sapiens
Interactions: 136
UniProt ID: O94842

Gene Ontology (top 5):
GO:0000785 - chromatin
GO:0001111 - RNA polymerase II promoter clearance
GO:0005634 - nucleus
GO:0006357 - regulation of transcription by RNA polymerase II
GO:0031490 - chromatin DNA binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

318529

TOX2
TOX high mobility group box family member 2

2

18

High-throughput

0.811

High

318468

PP1A
Serine/threonine-protein phosphatase PP1-alpha catalytic subunit

5

8

Small-scale

0.726

High

318469

PP1B
Serine/threonine-protein phosphatase PP1-beta catalytic subunit

5

8

Small-scale

0.723

High

318428

TBX6
T-box transcription factor TBX6

4

12

High-throughput

0.705

High

318530

PP1RA
Serine/threonine-protein phosphatase 1 regulatory subunit 10

4

8

Small-scale

0.699

High

318476

SSRP1
FACT complex subunit SSRP1

1

19

High-throughput

0.691

High

318453

PP1G
Serine/threonine-protein phosphatase PP1-gamma catalytic subunit

4

8

Small-scale

0.687

High

318512

BANP
Protein BANP

4

3

High-throughput

0.644

High

318498

WDR82
WD repeat-containing protein 82

2

17

Small-scale

0.639

High

318465

ATX1
Ataxin-1

2

10

High-throughput

0.620

High

318426

TOX4
TOX high mobility group box family member 4

1

17

Small-scale

0.618

High

318429

NSD2
Histone-lysine N-methyltransferase NSD2

1

16

Small-scale

0.618

High

318489

FND3B
Fibronectin type III domain-containing protein 3B

3

5

High-throughput

0.616

High

318452

FUS
RNA-binding protein FUS

2

14

High-throughput

0.611

High

318487

QRIC1
Transcriptional regulator QRICH1

2

12

High-throughput

0.606

High

276549

LX12B
Arachidonate 12-lipoxygenase, 12R-type

2

1

High-throughput

0.574

High

318463

SPB8
Serpin B8

2

10

High-throughput

0.574

High

318508

SPA12
Serpin A12

2

10

High-throughput

0.574

High

318435

HSPB1
Heat shock protein beta-1

1

4

High-throughput

0.541

High

318445

CREB1
Cyclic AMP-responsive element-binding protein 1

1

6

High-throughput

0.541

High

130336

SPT5H
Transcription elongation factor SPT5

1

18

High-throughput

0.536

High

251487

CCNT1
Cyclin-T1

1

7

High-throughput

0.536

High

316589

ST17B
Serine/threonine-protein kinase 17B

1

10

High-throughput

0.536

High

318427

HEXI1
Protein HEXIM1

1

5

High-throughput

0.536

High

318434

P53
Cellular tumor antigen p53

1

9

High-throughput

0.536

High

318438

SNRPA
U1 small nuclear ribonucleoprotein A

1

10

High-throughput

0.536

High

318439

RU1C
U1 small nuclear ribonucleoprotein C

1

1

High-throughput

0.536

High

318441

TOP1
DNA topoisomerase 1

1

9

High-throughput

0.536

High

318443

RSMB
Small nuclear ribonucleoprotein-associated proteins B and B'

1

4

High-throughput

0.536

High

318446

GATA3
Trans-acting T-cell-specific transcription factor GATA-3

1

15

High-throughput

0.536

High

318455

KDM5C
Lysine-specific demethylase 5C

1

7

High-throughput

0.536

High

318456

KI67
Proliferation marker protein Ki-67

1

12

High-throughput

0.536

High

318470

RUXF
Small nuclear ribonucleoprotein F

1

7

High-throughput

0.536

High

318480

SNW1
SNW domain-containing protein 1

1

3

High-throughput

0.536

High

318484

CPSF6
Cleavage and polyadenylation specificity factor subunit 6

1

19

High-throughput

0.536

High

318485

H2B2E
Histone H2B type 2-E

1

20

High-throughput

0.536

High

318474

MLRA
Myosin regulatory light chain 2, atrial isoform

1

2

High-throughput

0.523

High

318545

RHG26
Rho GTPase-activating protein 26

2

5

High-throughput

0.521

High

318507

KMT5C
Histone-lysine N-methyltransferase KMT5C

1

0

High-throughput

0.513

High

318537

HIPK3
Homeodomain-interacting protein kinase 3

1

17

High-throughput

0.508

High

318497

CCBE1
Collagen and calcium-binding EGF domain-containing protein 1

1

3

High-throughput

0.494

High

318462

KLK7
Kallikrein-7

1

4

High-throughput

0.489

High

318483

CYTM
Cystatin-M

1

1

High-throughput

0.489

High

318488

RA1L2
Heterogeneous nuclear ribonucleoprotein A1-like 2

1

20

High-throughput

0.489

High

318493

CTR9
RNA polymerase-associated protein CTR9 homolog

1

9

High-throughput

0.489

High

318499

PPR21
Protein phosphatase 1 regulatory subunit 21

1

1

High-throughput

0.489

High

318475

EXOSX
Exosome complex component 10

1

4

High-throughput

0.481

High

128684

MEN1
Menin

1

2

High-throughput

0.479

High

129627

CBX4
E3 SUMO-protein ligase CBX4

1

19

High-throughput

0.479

High

212118

SNUT1
U4/U6.U5 tri-snRNP-associated protein 1

1

7

High-throughput

0.479

High

228129

CPSF5
Cleavage and polyadenylation specificity factor subunit 5

1

2

High-throughput

0.479

High

252224

CCNT2
Cyclin-T2

1

7

High-throughput

0.479

High

318430

MYC
Myc proto-oncogene protein

1

18

High-throughput

0.479

High

318432

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

1

12

High-throughput

0.479

High

318433

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

6

High-throughput

0.479

High

318440

HSP7C
Heat shock cognate 71 kDa protein

1

5

High-throughput

0.479

High

318442

XRCC6
X-ray repair cross-complementing protein 6

1

6

High-throughput

0.479

High

318444

RFA2
Replication protein A 32 kDa subunit

1

7

High-throughput

0.479

High

318447

TYY1
Transcriptional repressor protein YY1

1

9

High-throughput

0.479

High

318448

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

9

High-throughput

0.479

High

318450

HSP74
Heat shock 70 kDa protein 4

1

8

Small-scale

0.479

High

318457

YAP1
Transcriptional coactivator YAP1

1

20

High-throughput

0.479

High

318458

KC1D
Casein kinase I isoform delta

1

5

High-throughput

0.479

High

318459

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

20

High-throughput

0.479

High

318464

CDK9
Cyclin-dependent kinase 9

1

15

High-throughput

0.479

High

318466

TERF1
Telomeric repeat-binding factor 1

1

5

High-throughput

0.479

High

318467

MFAP1
Microfibrillar-associated protein 1

1

2

High-throughput

0.479

High

318471

H4
Histone H4

1

12

High-throughput

0.479

High

318472

RED1
Double-stranded RNA-specific editase 1

1

10

High-throughput

0.479

High

318473

VIGLN
Vigilin

1

15

High-throughput

0.479

High

318477

RFA4
Replication protein A 30 kDa subunit

1

7

High-throughput

0.479

High

318478

PRP4K
Serine/threonine-protein kinase PRP4 homolog

1

20

High-throughput

0.479

High

318479

HDAC1
Histone deacetylase 1

1

20

High-throughput

0.479

High

318482

TERF2
Telomeric repeat-binding factor 2

1

5

High-throughput

0.479

High

318492

TAF2
Transcription initiation factor TFIID subunit 2

1

2

High-throughput

0.479

High

318501

MEPCE
7SK snRNA methylphosphate capping enzyme

1

3

High-throughput

0.479

High

318502

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

4

High-throughput

0.479

High

318503

NUFP2
FMR1-interacting protein NUFIP2

1

3

High-throughput

0.479

High

318504

HUWE1
E3 ubiquitin-protein ligase HUWE1

1

14

High-throughput

0.479

High

318505

NAA40
N-alpha-acetyltransferase 40

1

4

High-throughput

0.479

High

318506

DDX42
ATP-dependent RNA helicase DDX42

1

10

High-throughput

0.479

High

318509

SMC5
Structural maintenance of chromosomes protein 5

1

12

High-throughput

0.479

High

318510

SLX4
Structure-specific endonuclease subunit SLX4

1

13

High-throughput

0.479

High

318511

CPSF7
Cleavage and polyadenylation specificity factor subunit 7

1

4

High-throughput

0.479

High

318513

PR38A
Pre-mRNA-splicing factor 38A

1

1

High-throughput

0.479

High

318514

FA98A
Protein FAM98A

1

1

High-throughput

0.479

High

318515

RB15B
Putative RNA-binding protein 15B

1

10

High-throughput

0.479

High

318516

SNIP1
Smad nuclear-interacting protein 1

1

4

High-throughput

0.479

High

318519

PPIL4
Peptidyl-prolyl cis-trans isomerase-like 4

1

7

High-throughput

0.479

High

318522

PSPC1
Paraspeckle component 1

1

9

High-throughput

0.479

High

318523

TOPB1
DNA topoisomerase 2-binding protein 1

1

12

High-throughput

0.479

High

318525

ZBT10
Zinc finger and BTB domain-containing protein 10

1

18

Small-scale

0.479

High

318534

WWTR1
WW domain-containing transcription regulator protein 1

1

16

High-throughput

0.479

High

318535

NSRP1
Nuclear speckle splicing regulatory protein 1

1

7

High-throughput

0.479

High

318540

RAD18
E3 ubiquitin-protein ligase RAD18

1

1

High-throughput

0.479

High

318542

ZRAN1
Ubiquitin thioesterase ZRANB1

1

13

High-throughput

0.479

High

318543

RCOR1
REST corepressor 1

1

20

High-throughput

0.479

High

318527

Z512B
Zinc finger protein 512B

1

9

High-throughput

0.464

High

3464

A0A0S2Z5G4
Protein BANP

1

3

High-throughput

0.457

High

75639

B3KVV6
cDNA FLJ41607 fis, clone CTONG3001370, highly similar to Homo sapiens alpha-2-macroglobulin-like 1

1

7

High-throughput

0.437

High

217352

E41L2
Band 4.1-like protein 2

1

2

High-throughput

0.437

High

280439

PR40A
Pre-mRNA-processing factor 40 homolog A

1

18

High-throughput

0.437

High

318436

RPN1
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1

1

1

High-throughput

0.437

High

318437

VIME
Vimentin

1

6

Small-scale

0.437

High

318449

AMRP
Alpha-2-macroglobulin receptor-associated protein

1

1

High-throughput

0.437

High

318451

RFA3
Replication protein A 14 kDa subunit

1

6

High-throughput

0.437

High

318454

RS19
Small ribosomal subunit protein eS19

1

4

High-throughput

0.437

High

318461

RBM25
RNA-binding protein 25

1

14

High-throughput

0.437

High

318481

SRC8
Src substrate cortactin

1

8

High-throughput

0.437

High

318490

FA76B
Protein FAM76B

1

2

High-throughput

0.437

High

318494

RHDF2
Inactive rhomboid protein 2

1

2

High-throughput

0.437

High

318495

FIP1
Pre-mRNA 3'-end-processing factor FIP1

1

3

High-throughput

0.437

High

318500

TRI67
Tripartite motif-containing protein 67

1

13

High-throughput

0.437

High

318517

FA76A
Protein FAM76A

1

2

High-throughput

0.437

High

318518

RHBL4
Rhomboid-related protein 4

1

2

High-throughput

0.437

High

318520

ATX2L
Ataxin-2-like protein

1

20

High-throughput

0.437

High

318524

PF21A
PHD finger protein 21A

1

20

High-throughput

0.437

High

318531

POP1
Ribonucleases P/MRP protein subunit POP1

1

2

High-throughput

0.437

High

318533

MMTA2
Multiple myeloma tumor-associated protein 2

1

1

High-throughput

0.437

High

318538

PKHA4
Pleckstrin homology domain-containing family A member 4

1

6

High-throughput

0.437

High

318539

MET17
Ribosome assembly protein METTL17, mitochondrial

1

1

High-throughput

0.437

High

318541

KBTB4
Kelch repeat and BTB domain-containing protein 4

1

5

High-throughput

0.437

High

318544

HECD1
E3 ubiquitin-protein ligase HECTD1

1

17

High-throughput

0.437

High

75858

B4DE54
Protein BANP

1

3

High-throughput

0.417

High

69460

A2ML1
Alpha-2-macroglobulin-like protein 1

1

7

High-throughput

0.407

High

318528

CEP63
Centrosomal protein of 63 kDa

1

7

High-throughput

0.407

High

318526

ZMY19
Zinc finger MYND domain-containing protein 19

3

0

High-throughput

0.352

High

318431

IFNA1
Interferon alpha-1/13

2

0

High-throughput

0.328

High

318491

KPRP
Keratinocyte proline-rich protein

2

0

High-throughput

0.328

High

318521

GEMI6
Gem-associated protein 6

1

0

High-throughput

0.299

High

318460

SRP09
Signal recognition particle 9 kDa protein

1

0

High-throughput

0.279

Low

318496

SBSN
Suprabasin

1

0

High-throughput

0.279

Low

318486

PPR3A
Protein phosphatase 1 regulatory subunit 3A

1

0

High-throughput

0.249

Low

318532

TACO1
Translational activator of cytochrome c oxidase 1

1

0

High-throughput

0.249

Low

318536

TXNIP
Thioredoxin-interacting protein

1

0

Small-scale

0.249

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025