HitPredict

Interactor 1: M4K4 (O95819)
Mitogen-activated protein kinase kinase kinase kinase 4 (EC 2.7.11.1) (HPK/GCK-like kinase HGK) (MAPK/ERK kinase kinase kinase 4) (MEK kinase kinase 4) (MEKKK 4) (Nck-interacting kinase)
Gene: MAP4K4

Interactor 2: UBE2H (P62256)
Ubiquitin-conjugating enzyme E2 H (EC 2.3.2.23) ((E3-independent) E2 ubiquitin-conjugating enzyme H) (EC 2.3.2.24) (E2 ubiquitin-conjugating enzyme H) (UbcH2) (Ubiquitin carrier protein H) (Ubiquitin-conjugating enzyme E2-20K) (Ubiquitin-protein ligase H)
Gene: UBE2H

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	38113892
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 1239 Hs			1 183
+	Hs
		829083 TNIK_HUMAN (1-1239): 0: 1101: 60.56		UBE2A_HUMAN (4-150): 8.87e-65: 197: 30.46
+	Hs
		909353 MAST1_HUMAN (3-947): 3.96e-126: 426: 14.68		UBE2H_HUMAN (1-183): 8.84e-64: 196: 100.00
+	Hs
		647861 MARK3_HUMAN (16-665): 4.1e-127: 411: 16.23		UBE2H_HUMAN (1-183): 8.84e-64: 196: 100.00
+	Hs
		908733 MARK2_HUMAN (8-669): 2.09e-122: 399: 14.10		UBE2H_HUMAN (1-183): 8.84e-64: 196: 100.00
+	Hs
		682160 AKT2_HUMAN (2-354): 7.38e-124: 393: 21.98		UBE2H_HUMAN (1-183): 8.84e-64: 196: 100.00
+	Hs
		908467 AAPK1_HUMAN (8-555): 9.95e-123: 392: 16.85		UBE2H_HUMAN (1-183): 8.84e-64: 196: 100.00
+	Hs
		131560 STK25_HUMAN (14-452): 5.34e-114: 364: 34.99		UB2D3_HUMAN (7-150): 5.39e-71: 213: 29.05
+	Hs
		908460 STK4_HUMAN (4-517): 8.55e-119: 379: 31.92		UBE2H_HUMAN (1-183): 8.84e-64: 196: 100.00