Interactor 1: CDK2 (P24941)
Cyclin-dependent kinase 2 (EC 2.7.11.22) (Cell division protein kinase 2) (p33 protein kinase)
Gene: CDK2

Interactor 2: UHRF2 (Q96PU4)
E3 ubiquitin-protein ligase UHRF2 (EC 2.3.2.27) (Np95/ICBP90-like RING finger protein) (Np95-like RING finger protein) (Nuclear protein 97) (Nuclear zinc finger protein Np97) (RING finger protein 107) (RING-type E3 ubiquitin transferase UHRF2) (Ubiquitin-like PHD and RING finger domain-containing protein 2) (Ubiquitin-like-containing PHD and RING finger domains protein 2)
Gene: UHRF2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.79 1.00 0.892

The method score is based on:

Property Details
Experiments 33876395, 21952639, 15178429
Identification Methods affinity chromatography technology, far western blotting, enzymatic study, antibody array, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation, pull down, protein kinase assay
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains Pkinase~ubiquitin
Common GO terms GO:0005634 - nucleus
GO:0005654 - nucleoplasm
Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 298
Hs

1 802
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024