Protein: HEXI2
Protein HEXIM2 (Hexamethylene bis-acetamide-inducible protein 2)

Gene: HEXI2, HEXIM2
Organism: Homo sapiens
Interactions: 89
UniProt ID: Q96MH2

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0004861 - cyclin-dependent protein serine/threonine kinase inhibitor activity
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

325054

HEXI1
Protein HEXIM1

8

2

Small-scale

0.965

High

1398168

HEXI2
Protein HEXIM2

4

2

High-throughput

0.900

High

897942

CDK9
Cyclin-dependent kinase 9

11

12

Small-scale

0.757

High

1398172

HTF4
Transcription factor 12

6

1

High-throughput

0.741

High

230091

SAHH2
S-adenosylhomocysteine hydrolase-like protein 1

4

4

High-throughput

0.698

High

1271799

MEPCE
7SK snRNA methylphosphate capping enzyme

4

1

High-throughput

0.694

High

1194293

LARP7
La-related protein 7

4

7

Small-scale

0.687

High

1109359

PIN1
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1

3

1

High-throughput

0.675

High

251642

CCNT1
Cyclin-T1

3

4

High-throughput

0.667

High

587187

ITF2
Transcription factor 4

3

1

High-throughput

0.667

High

995203

CSK2B
Casein kinase II subunit beta

3

1

High-throughput

0.667

High

1145330

RNPS1
RNA-binding protein with serine-rich domain 1

3

7

High-throughput

0.654

High

1398175

PRD14
PR domain zinc finger protein 14

2

2

High-throughput

0.640

High

894098

MEOX2
Homeobox protein MOX-2

2

1

High-throughput

0.633

High

252263

CCNT2
Cyclin-T2

2

4

High-throughput

0.628

High

625566

CSK22
Casein kinase II subunit alpha'

2

7

High-throughput

0.628

High

997951

CSK21
Casein kinase II subunit alpha

2

6

High-throughput

0.628

High

1149674

SURF2
Surfeit locus protein 2

2

1

High-throughput

0.628

High

1371506

USP9X
Ubiquitin carboxyl-terminal hydrolase 9X

2

2

High-throughput

0.628

High

1393305

SAHH3
Adenosylhomocysteinase 3

2

4

High-throughput

0.628

High

1398170

FER3L
Fer3-like protein

2

2

High-throughput

0.628

High

138751

IMA4
Importin subunit alpha-4

2

1

High-throughput

0.606

High

245034

ZN500
Zinc finger protein 500

2

1

High-throughput

0.606

High

680989

PSA1
Proteasome subunit alpha type-1

2

5

High-throughput

0.606

High

885370

HXA1
Homeobox protein Hox-A1

2

2

High-throughput

0.606

High

1121306

TRI14
Tripartite motif-containing protein 14

2

1

High-throughput

0.606

High

1181216

ZN699
Zinc finger protein 699

2

1

High-throughput

0.606

High

1204449

ZN789
Zinc finger protein 789

2

1

High-throughput

0.606

High

1279702

SPRE1
Sprouty-related, EVH1 domain-containing protein 1

2

3

High-throughput

0.606

High

1330210

ZN655
Zinc finger protein 655

2

1

High-throughput

0.606

High

1386672

AP2M1
AP-2 complex subunit mu

2

3

High-throughput

0.606

High

1398169

ZN558
Zinc finger protein 558

2

2

High-throughput

0.606

High

1398174

ZN426
Zinc finger protein 426

2

2

High-throughput

0.606

High

839611

HUTH
Histidine ammonia-lyase

2

0

High-throughput

0.602

High

1307385

RIOX2
Ribosomal oxygenase 2

2

0

High-throughput

0.602

High

1332015

BANP
Protein BANP

2

0

High-throughput

0.602

High

1398173

MYCBP
c-Myc-binding protein

2

0

High-throughput

0.602

High

140408

SDCB1
Syntenin-1

2

0

High-throughput

0.580

High

213483

CTIF
CBP80/20-dependent translation initiation factor

2

0

High-throughput

0.580

High

269347

HSF2B
Heat shock factor 2-binding protein

2

0

High-throughput

0.580

High

353733

DRC4
Dynein regulatory complex subunit 4

2

0

High-throughput

0.580

High

1061829

TLE5
TLE family member 5

2

0

High-throughput

0.580

High

1117916

BACD2
BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 2

2

0

High-throughput

0.580

High

1185308

F161A
Protein FAM161A

2

0

High-throughput

0.580

High

1187738

KR133
Keratin-associated protein 13-3

2

0

High-throughput

0.580

High

1213811

KPRP
Keratinocyte proline-rich protein

2

0

High-throughput

0.580

High

1339490

DBF4B
Protein DBF4 homolog B

2

0

High-throughput

0.580

High

1348434

LNX1
E3 ubiquitin-protein ligase LNX

2

0

High-throughput

0.580

High

1398176

PICK1
PRKCA-binding protein

2

0

High-throughput

0.580

High

928524

TERF1
Telomeric repeat-binding factor 1

1

3

High-throughput

0.573

High

221170

SPY2
Protein sprouty homolog 2

1

2

High-throughput

0.573

High

221388

SPY1
Protein sprouty homolog 1

1

2

High-throughput

0.573

High

541051

PIM1
Serine/threonine-protein kinase pim-1

1

2

High-throughput

0.573

High

699469

PROP
Properdin

2

1

High-throughput

0.553

High

1149966

TERF2
Telomeric repeat-binding factor 2

1

3

High-throughput

0.552

High

284866

TADA3
Transcriptional adapter 3

1

0

High-throughput

0.549

High

590480

GATA1
Erythroid transcription factor

1

0

High-throughput

0.549

High

1398177

KLHL9
Kelch-like protein 9

1

3

High-throughput

0.536

High

1398178

KLH13
Kelch-like protein 13

1

3

High-throughput

0.536

High

1398182

NGN3
Neurogenin-3

1

3

High-throughput

0.536

High

92343

D3DU92
RNA-binding protein with serine-rich domain 1

1

7

High-throughput

0.515

High

1232525

Q6FHY5
MEOX2 protein

1

1

High-throughput

0.515

High

832325

ID1
DNA-binding protein inhibitor ID-1

1

0

High-throughput

0.513

High

1398171

CK5P1
Mitochondrial tRNA methylthiotransferase CDK5RAP1

1

0

High-throughput

0.513

High

605216

TAL1
T-cell acute lymphocytic leukemia protein 1

1

3

High-throughput

0.500

High

1037884

HEN1
Helix-loop-helix protein 1

1

3

High-throughput

0.500

High

585086

ZN250
Zinc finger protein 250

1

1

High-throughput

0.481

High

173240

XPO1
Exportin-1

1

1

High-throughput

0.479

High

401319

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

2

High-throughput

0.479

High

472991

RU17
U1 small nuclear ribonucleoprotein 70 kDa

1

7

High-throughput

0.479

High

636131

CD11B
Cyclin-dependent kinase 11B

1

5

High-throughput

0.479

High

1141871

EEA1
Early endosome antigen 1

1

2

High-throughput

0.479

High

1398179

ZRAN1
Ubiquitin thioesterase ZRANB1

1

1

High-throughput

0.479

High

1398181

CD11A
Cyclin-dependent kinase 11A

1

5

High-throughput

0.479

High

332568

CCDB1
Cyclin-D1-binding protein 1

1

0

High-throughput

0.458

High

959516

YPEL3
Protein yippee-like 3

1

1

High-throughput

0.439

High

603678

JUNB
Transcription factor JunB

1

0

High-throughput

0.426

High

725535

KAP3
cAMP-dependent protein kinase type II-beta regulatory subunit

1

0

High-throughput

0.426

High

1281045

TAF8
Transcription initiation factor TFIID subunit 8

1

0

High-throughput

0.426

High

1385134

MOAP1
Modulator of apoptosis 1

1

0

High-throughput

0.426

High

1062942

CACB2
Voltage-dependent L-type calcium channel subunit beta-2

2

0

High-throughput

0.316

High

1250287

ATL4
ADAMTS-like protein 4

2

0

High-throughput

0.316

High

1315738

SAXO1
Stabilizer of axonemal microtubules 1

2

0

High-throughput

0.316

High

1398180

EGFL7
Epidermal growth factor-like protein 7

2

0

High-throughput

0.316

High

1314603

IHO1
Interactor of HORMAD1 protein 1

1

0

High-throughput

0.299

High

1387799

MUCL1
Mucin-like protein 1

1

0

High-throughput

0.279

Low

1328391

CCD33
Coiled-coil domain-containing protein 33

1

0

High-throughput

0.251

Low

1309552

NNRD
ATP-dependent

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025