HitPredict

Interactor 1: LATS1 (O95835)
Serine/threonine-protein kinase LATS1 (EC 2.7.11.1) (Large tumor suppressor homolog 1) (WARTS protein kinase) (h-warts)
Gene: LATS1

Interactor 2: INADL (Q8NI35)
InaD-like protein (Inadl protein) (hINADL) (Channel-interacting PDZ domain-containing protein) (Pals1-associated tight junction protein) (Protein associated to tight junctions)
Gene: PATJ

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	34079125, 24255178
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 1130 Hs			1 1801
+	Hs
		1246440 LATS2_HUMAN (13-1121): 0: 751: 49.61		INADL_HUMAN (1-1801): 0: 1090: 100.00
+	Hs
		325772 LATS1_HUMAN (1-1130): 0: 934: 100.00		MAGI3_HUMAN (220-1111): 5.81e-37: 155: 13.46
+	Hs
		280011 LATS1_HUMAN (1-1130): 0: 934: 100.00		MPDZ_HUMAN (1494-1800): 2.48e-27: 124: 20.19
+	Hs
		325709 LATS1_HUMAN (1-1130): 0: 934: 100.00		PTN13_HUMAN (312-1336): 3.39e-25: 117: 12.43
+	Hs
		325859 LATS1_HUMAN (1-1130): 0: 934: 100.00		MAGI1_HUMAN (1-258): 2.32e-19: 97.8: 15.50
+	Hs
		325729 LATS1_HUMAN (1-1130): 0: 934: 100.00		SCRIB_HUMAN (142-438): 1.73e-10: 68.6: 26.78
+	Hs
		280078 LATS2_HUMAN (13-1121): 0: 751: 49.61		MPDZ_HUMAN (1494-1800): 2.48e-27: 124: 20.19
+	Hs
		1020225 LATS2_HUMAN (13-1121): 0: 751: 49.61		PTN13_HUMAN (312-1336): 3.39e-25: 117: 12.43
+	Hs
		1300675 LATS2_HUMAN (13-1121): 0: 751: 49.61		MAGI1_HUMAN (1-258): 2.32e-19: 97.8: 15.50
+	Hs
		1344984 LATS2_HUMAN (13-1121): 0: 751: 49.61		GRIP1_HUMAN (5-256): 2.15e-17: 90.9: 13.99
+	Hs
		1232910 LATS2_HUMAN (13-1121): 0: 751: 49.61		LNX2_HUMAN (1590-1794): 8.05e-16: 85.5: 19.16
+	Ce
		88187 WARTS_CAEEL (397-1088): 1.32e-154: 486: 35.43		D3YT29_CAEEL (4-221): 1.81e-20: 100: 17.81
+	Mm
		933108 KAPCB_MOUSE (661-1056): 2.81e-133: 410: 32.25		DLG4_MOUSE (503-837): 8.4e-23: 107: 16.47
+	Mm
		936586 ROCK2_MOUSE (694-1046): 5.43e-62: 234: 38.27		DLG4_MOUSE (503-837): 8.4e-23: 107: 16.47