HitPredict

Interactor 1: LATS1 (O95835)
Serine/threonine-protein kinase LATS1 (EC 2.7.11.1) (Large tumor suppressor homolog 1) (WARTS protein kinase) (h-warts)
Gene: LATS1

Interactor 2: MAGI1 (Q96QZ7)
Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 (Atrophin-1-interacting protein 3) (AIP-3) (BAI1-associated protein 1) (BAP-1) (Membrane-associated guanylate kinase inverted 1) (MAGI-1) (Trinucleotide repeat-containing gene 19 protein) (WW domain-containing protein 3) (WWP3)
Gene: MAGI1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	34079125, 24255178
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1130 Hs			1 1491
+	Hs
		1300675 LATS2_HUMAN (13-1121): 0: 751: 49.61		MAGI1_HUMAN (1-1491): 0: 756: 100.00
+	Hs
		325709 LATS1_HUMAN (1-1130): 0: 934: 100.00		PTN13_HUMAN (227-1419): 7.85e-57: 220: 10.78
+	Hs
		280011 LATS1_HUMAN (1-1130): 0: 934: 100.00		MPDZ_HUMAN (17-101): 2.83e-15: 84.1: 27.27
+	Hs
		325937 LATS1_HUMAN (1-1130): 0: 934: 100.00		WWC3_HUMAN (301-430): 3.58e-15: 83.6: 35.37
+	Hs
		325797 LATS1_HUMAN (1-1130): 0: 934: 100.00		KIBRA_HUMAN (301-430): 4.15e-15: 83.2: 34.04
+	Hs
		125071 LATS1_HUMAN (1-1130): 0: 934: 100.00		WWP2_HUMAN (215-434): 9.36e-15: 82: 29.39
+	Hs
		325775 LATS1_HUMAN (1-1130): 0: 934: 100.00		WWC2_HUMAN (291-423): 9.32e-15: 82: 37.78
+	Hs
		325825 LATS1_HUMAN (1-1130): 0: 934: 100.00		PARD3_HUMAN (362-806): 5.29e-13: 76.6: 16.74
+	Hs
		325820 LATS1_HUMAN (1-1130): 0: 934: 100.00		INADL_HUMAN (14-131): 7.48e-13: 76: 14.75
+	Hs
		325772 LATS1_HUMAN (1-1130): 0: 934: 100.00		MAGI3_HUMAN (2-688): 2.39e-12: 74.4: 11.08
+	Hs
		325729 LATS1_HUMAN (1-1130): 0: 934: 100.00		SCRIB_HUMAN (838-1232): 4.22e-09: 63.5: 23.26
+	Hs
		1020225 LATS2_HUMAN (13-1121): 0: 751: 49.61		PTN13_HUMAN (227-1419): 7.85e-57: 220: 10.78
+	Hs
		1232910 LATS2_HUMAN (13-1121): 0: 751: 49.61		LNX2_HUMAN (143-717): 3.54e-21: 102: 12.44
+	Hs
		280078 LATS2_HUMAN (13-1121): 0: 751: 49.61		MPDZ_HUMAN (17-101): 2.83e-15: 84.1: 27.27
+	Hs
		1344970 LATS2_HUMAN (13-1121): 0: 751: 49.61		WWC3_HUMAN (301-430): 3.58e-15: 83.6: 35.37
+	Hs
		1220087 LATS2_HUMAN (13-1121): 0: 751: 49.61		KIBRA_HUMAN (301-430): 4.15e-15: 83.2: 34.04
+	Hs
		1149656 LATS2_HUMAN (13-1121): 0: 751: 49.61		WWC2_HUMAN (291-423): 9.32e-15: 82: 37.78
+	Hs
		1256906 LATS2_HUMAN (13-1121): 0: 751: 49.61		PARD3_HUMAN (362-806): 5.29e-13: 76.6: 16.74
+	Hs
		1246440 LATS2_HUMAN (13-1121): 0: 751: 49.61		INADL_HUMAN (14-131): 7.48e-13: 76: 14.75
+	Hs
		1344984 LATS2_HUMAN (13-1121): 0: 751: 49.61		GRIP1_HUMAN (1119-1243): 8.92e-11: 69.1: 21.26