HitPredict

Interactor 1: UBR5 (O95071)
E3 ubiquitin-protein ligase UBR5 (EC 2.3.2.26) (E3 ubiquitin-protein ligase, HECT domain-containing 1) (Hyperplastic discs protein homolog) (hHYD) (Progestin-induced protein)
Gene: UBR5

Interactor 2: GFI1B (Q5VTD9)
Zinc finger protein Gfi-1b (Growth factor independent protein 1B) (Potential regulator of CDKN1A translocated in CML)
Gene: GFI1B

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	30894540
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0008270 - zinc ion binding
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 2799 Hs			1 330
+	Hs
		325676 UBR5_HUMAN (1-2799): 0: 3949: 100.00		ZNF7_HUMAN (51-330): 1.43e-106: 327: 26.11
+	Hs
		325948 UBR5_HUMAN (1-2799): 0: 3949: 100.00		ZN480_HUMAN (2-216): 2.22e-79: 253: 17.33
+	Hs
		326087 UBR5_HUMAN (1-2799): 0: 3949: 100.00		ZN180_HUMAN (131-330): 9.71e-64: 215: 24.73
+	Hs
		325808 UBR5_HUMAN (1-2799): 0: 3949: 100.00		ZN543_HUMAN (2-191): 1.2e-52: 184: 12.50
+	Hs
		325675 UBR5_HUMAN (1-2799): 0: 3949: 100.00		ZNF3_HUMAN (4-219): 2.62e-49: 172: 16.52
+	Hs
		326007 UBR5_HUMAN (1-2799): 0: 3949: 100.00		ZN577_HUMAN (52-245): 1.85e-48: 170: 22.07
+	Hs
		1217732 HECW1_HUMAN (2170-2798): 2.45e-168: 568: 20.31		GFI1B_HUMAN (1-330): 5.91e-118: 345: 100.00
+	Hs
		1132513 WWP1_HUMAN (2180-2797): 2.85e-126: 425: 18.43		ZN846_HUMAN (174-322): 1.94e-09: 60.5: 28.19
+	Hs
		585020 UBE3A_HUMAN (2529-2799): 7.91e-20: 99.4: 29.93		ZN250_HUMAN (2-185): 4.29e-47: 168: 10.22