HitPredict

Interactor 1: LATS1 (O95835)
Serine/threonine-protein kinase LATS1 (EC 2.7.11.1) (Large tumor suppressor homolog 1) (WARTS protein kinase) (h-warts)
Gene: LATS1

Interactor 2: CP131 (Q9UPN4)
Centrosomal protein of 131 kDa (5-azacytidine-induced protein 1) (Pre-acrosome localization protein 1)
Gene: CEP131

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	34079125, 24255178
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005813 - centrosome GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1130 Hs			1 1083
+	Hs
		325935 LATS1_HUMAN (1-1130): 0: 934: 100.00		MYH2_HUMAN (165-1083): 6.52e-39: 160: 9.54
+	Hs
		325605 LATS1_HUMAN (1-1130): 0: 934: 100.00		MYH3_HUMAN (239-1083): 1.05e-33: 143: 10.00
+	Hs
		325611 LATS1_HUMAN (1-1130): 0: 934: 100.00		MYH6_HUMAN (401-1083): 1.84e-23: 110: 10.69
+	Hs
		325936 LATS1_HUMAN (1-1130): 0: 934: 100.00		MYH13_HUMAN (407-1083): 1.56e-23: 110: 11.54
+	Hs
		325609 LATS1_HUMAN (1-1130): 0: 934: 100.00		MYH7_HUMAN (454-1078): 2.77e-22: 106: 13.38
+	Hs
		325608 LATS1_HUMAN (1-1130): 0: 934: 100.00		MYH1_HUMAN (454-1082): 4.06e-22: 105: 10.81
+	Hs
		325955 LATS1_HUMAN (1-1130): 0: 934: 100.00		MYH4_HUMAN (454-1054): 3.45e-20: 99.5: 11.86
+	Hs
		325737 LATS1_HUMAN (1-1130): 0: 934: 100.00		PLEC_HUMAN (237-915): 7.61e-17: 88.6: 13.48
+	Hs
		325612 LATS1_HUMAN (1-1130): 0: 934: 100.00		MYH8_HUMAN (119-702): 1.2e-16: 88: 7.30
+	Hs
		1344975 LATS2_HUMAN (13-1121): 0: 751: 49.61		CP131_HUMAN (664-1083): 1.02e-11: 71.4: 11.40
+	Hs
		725079 ST38L_HUMAN (627-1089): 2.37e-167: 503: 40.82		MYH9_HUMAN (117-841): 6.25e-23: 108: 9.26
+	Hs
		610795 KAPCB_HUMAN (661-1055): 5.19e-133: 410: 31.58		MYH2_HUMAN (165-1083): 6.52e-39: 160: 9.54
+	Hs
		681696 AKT1_HUMAN (595-1081): 5.84e-141: 435: 24.50		MYH9_HUMAN (117-841): 6.25e-23: 108: 9.26
+	Hs
		568567 KAPCA_HUMAN (661-1058): 6.14e-138: 422: 31.59		MYH9_HUMAN (117-841): 6.25e-23: 108: 9.26
+	Hs
		528359 KAPCB_HUMAN (661-1055): 5.19e-133: 410: 31.58		MYH6_HUMAN (401-1083): 1.84e-23: 110: 10.69
+	Hs
		522538 KAPCB_HUMAN (661-1055): 5.19e-133: 410: 31.58		MYH1_HUMAN (454-1082): 4.06e-22: 105: 10.81
+	Hs
		610802 KAPCB_HUMAN (661-1055): 5.19e-133: 410: 31.58		MYH4_HUMAN (454-1054): 3.45e-20: 99.5: 11.86
+	Hs
		568568 KAPCA_HUMAN (661-1058): 6.14e-138: 422: 31.59		MYH10_HUMAN (115-657): 3.26e-14: 79.9: 9.29
+	Hs
		724810 ROCK1_HUMAN (694-1046): 9.23e-66: 245: 39.94		MYH9_HUMAN (117-841): 6.25e-23: 108: 9.26
+	Hs
		1137917 MRCKA_HUMAN (694-1047): 2.92e-66: 248: 39.06		MRCKB_HUMAN (228-728): 8.99e-12: 72: 11.27