HitPredict

Interactor 1: TSN15 (O95858)
Tetraspanin-15 (Tspan-15) (Tetraspan NET-7) (Transmembrane 4 superfamily member 15)
Gene: TSPAN15

Interactor 2: CD63 (P08962)
CD63 antigen (Granulophysin) (Lysosomal-associated membrane protein 3) (LAMP-3) (Lysosome integral membrane protein 1) (Limp1) (Melanoma-associated antigen ME491) (OMA81H) (Ocular melanoma-associated antigen) (Tetraspanin-30) (Tspan-30) (CD antigen CD63)
Gene: CD63

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	1.00	0.691

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Tetraspanin~Tetraspanin
Common GO terms	GO:0005886 - plasma membrane GO:0009986 - cell surface GO:0031902 - late endosome membrane GO:0043231 - intracellular membrane-bounded organelle
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 294 Hs			1 238
+	Hs
		209300 TSN15_HUMAN (1-294): 9.34e-96: 285: 100.00		TSN6_HUMAN (1-238): 1.26e-64: 202: 28.33
+	Hs
		326051 TSN15_HUMAN (1-294): 9.34e-96: 285: 100.00		TSN5_HUMAN (7-235): 4.96e-63: 199: 25.20
+	Hs
		326042 TSN15_HUMAN (1-294): 9.34e-96: 285: 100.00		CD151_HUMAN (3-232): 2.85e-60: 191: 28.22
+	Hs
		326141 TSN15_HUMAN (1-294): 9.34e-96: 285: 100.00		TSN14_HUMAN (11-235): 5.91e-59: 189: 27.60
+	Hs
		279367 TSN15_HUMAN (1-294): 9.34e-96: 285: 100.00		TSN9_HUMAN (4-233): 2.1e-57: 184: 30.04
+	Hs
		326023 TSN15_HUMAN (1-294): 9.34e-96: 285: 100.00		CD9_HUMAN (1-238): 1.72e-54: 176: 24.49
+	Hs
		326050 TSN15_HUMAN (1-294): 9.34e-96: 285: 100.00		CD81_HUMAN (1-234): 5.88e-53: 172: 21.63
+	Hs
		237776 TSN15_HUMAN (1-294): 9.34e-96: 285: 100.00		TSN3_HUMAN (4-236): 4.09e-48: 160: 29.17
+	Hs
		819445 TSN5_HUMAN (7-266): 9.73e-80: 244: 32.58		CD151_HUMAN (3-232): 2.85e-60: 191: 28.22
+	Hs
		905534 TSN5_HUMAN (7-266): 9.73e-80: 244: 32.58		TSN14_HUMAN (11-235): 5.91e-59: 189: 27.60
+	Hs
		279369 TSN5_HUMAN (7-266): 9.73e-80: 244: 32.58		TSN9_HUMAN (4-233): 2.1e-57: 184: 30.04
+	Hs
		819462 TSN14_HUMAN (9-268): 5.26e-77: 237: 31.46		CD151_HUMAN (3-232): 2.85e-60: 191: 28.22
+	Hs
		602239 TSN5_HUMAN (7-266): 9.73e-80: 244: 32.58		CD9_HUMAN (1-238): 1.72e-54: 176: 24.49
+	Hs
		887767 TSN5_HUMAN (7-266): 9.73e-80: 244: 32.58		CD81_HUMAN (1-234): 5.88e-53: 172: 21.63
+	Hs
		602271 TSN14_HUMAN (9-268): 5.26e-77: 237: 31.46		CD9_HUMAN (1-238): 1.72e-54: 176: 24.49
+	Hs
		887904 TSN14_HUMAN (9-268): 5.26e-77: 237: 31.46		CD81_HUMAN (1-234): 5.88e-53: 172: 21.63
+	Ce
		1094902 TSP12_CAEEL (7-270): 2.27e-64: 206: 24.91		TSP21_CAEEL (13-206): 5.18e-15: 74.3: 27.27