Interactor 1: BCL10 (O95999)
B-cell lymphoma/leukemia 10 (B-cell CLL/lymphoma 10) (Bcl-10) (CARD-containing molecule enhancing NF-kappa-B) (CARD-like apoptotic protein) (hCLAP) (CED-3/ICH-1 prodomain homologous E10-like regulator) (CIPER) (Cellular homolog of vCARMEN) (cCARMEN) (Cellular-E10) (c-E10) (Mammalian CARD-containing adapter molecule E10) (mE10)
Gene: BCL10
Interactor 2: CARD9 (Q9H257)
Caspase recruitment domain-containing protein 9 (hCARD9)
Gene: CARD9
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.89 | 1.00 | 0.945 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 11053425, 28765954, 33789983, 22423967, 25416956, 22267217 |
| Identification Methods | two hybrid, pull down, affinity chromatography technology, anti tag coimmunoprecipitation, mammalian protein protein interaction trap, anti bait coimmunoprecipitation |
| Interaction Type | direct interaction, physical association, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | CARD~CARD |
| Common GO terms | GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0016064 - immunoglobulin mediated immune response GO:0032449 - CBM complex GO:0032755 - positive regulation of interleukin-6 production and 7 others more... |
| Homologous interactions | 6 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
