HitPredict

Interactor 1: LDHA (P00338)
L-lactate dehydrogenase A chain (LDH-A) (EC 1.1.1.27) (Cell proliferation-inducing gene 19 protein) (LDH muscle subunit) (LDH-M) (Renal carcinoma antigen NY-REN-59)
Gene: LDHA

Interactor 2: CFTR (P13569)
Cystic fibrosis transmembrane conductance regulator (CFTR) (ATP-binding cassette sub-family C member 7) (Channel conductance-controlling ATPase) (EC 5.6.1.6) (cAMP-dependent chloride channel)
Gene: CFTR

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.73	0.60	0.662

Property	Details
Experiments	26618866, 31324722, 29924966
Identification Methods	affinity chromatography technology, pull down, cross-linking study, anti bait coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol GO:0016020 - membrane
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 332 Hs			1 1480
+	Hs
		529308 LDH6A_HUMAN (1-332): 6.69e-153: 434: 73.49		CFTR_HUMAN (1-1480): 0: 1031: 100.00
+	Hs
		421957 LDHB_HUMAN (1-331): 9.03e-153: 433: 75.30		CFTR_HUMAN (1-1480): 0: 1031: 100.00
+	Hs
		528711 MDHM_HUMAN (1-332): 1.4e-108: 321: 19.19		CFTR_HUMAN (1-1480): 0: 1031: 100.00
+	Hs
		528710 MDHC_HUMAN (22-332): 6.85e-107: 317: 21.23		CFTR_HUMAN (1-1480): 0: 1031: 100.00
+	Hs
		238937 LDHA_HUMAN (1-332): 7.2e-159: 449: 100.00		ABCC9_HUMAN (1213-1430): 7.34e-10: 66.2: 23.71