HitPredict

Interactor 1: SVIL (O95425)
Supervillin (Archvillin) (p205/p250)
Gene: SVIL

Interactor 2: 1433T (P27348)
14-3-3 protein theta (14-3-3 protein T-cell) (14-3-3 protein tau) (Protein HS1)
Gene: YWHAQ

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.571

Property	Details
Experiments	36931259, unassigned3799
Identification Methods	proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0005925 - focal adhesion
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 2214 Hs			1 245
+	Hs
		336390 SVIL_HUMAN (1-2214): 0: 3444: 100.00		1433E_HUMAN (2-243): 1.32e-144: 406: 63.53
+	Hs
		336397 SVIL_HUMAN (1-2214): 0: 3444: 100.00		1433Z_HUMAN (1-245): 1.76e-141: 397: 79.59
+	Hs
		336356 SVIL_HUMAN (1-2214): 0: 3444: 100.00		1433B_HUMAN (1-242): 5.04e-139: 391: 81.82
+	Hs
		336357 SVIL_HUMAN (1-2214): 0: 3444: 100.00		1433S_HUMAN (1-236): 9.9e-108: 312: 71.85
+	Hs
		336410 SVIL_HUMAN (1-2214): 0: 3444: 100.00		1433F_HUMAN (2-242): 7.19e-106: 307: 71.43
+	Hs
		336387 SVIL_HUMAN (1-2214): 0: 3444: 100.00		1433G_HUMAN (1-242): 5.51e-105: 305: 70.33
+	Mm
		559565 GELS_MOUSE (1723-2122): 6.2e-83: 293: 18.40		1433Z_MOUSE (1-245): 3.08e-142: 399: 80.00
+	At
		307369 VILI3_ARATH (1754-2189): 5.13e-64: 240: 20.54		14333_ARATH (3-243): 8.04e-143: 401: 61.63
+	At
		307368 VILI3_ARATH (1754-2189): 5.13e-64: 240: 20.54		14331_ARATH (3-242): 2.68e-142: 400: 61.07
+	At
		307367 VILI2_ARATH (1461-2214): 8.25e-26: 118: 15.36		14332_ARATH (3-243): 8.69e-144: 404: 61.22