Interactor 1: EGFR (P00533)
Epidermal growth factor receptor (EC 2.7.10.1) (Proto-oncogene c-ErbB-1) (Receptor tyrosine-protein kinase erbB-1)
Gene: EGFR

Interactor 2: GPNMB (Q14956)
Transmembrane glycoprotein NMB (Hematopoietic growth factor inducible neurokinin-1 type)
Gene: GPNMB

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.57 0.55 0.564

The method score is based on:

Property Details
Experiments 26751287
Identification Methods enzymatic study, anti bait coimmunoprecipitation, pull down, anti tag coimmunoprecipitation
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0001934 - positive regulation of protein phosphorylation
GO:0005178 - integrin binding
GO:0005886 - plasma membrane
GO:0007165 - signal transduction
GO:0016020 - membrane
and 3 others

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Homologous interactions 0

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024