Protein: FBXL2
F-box/LRR-repeat protein 2 (F-box and leucine-rich repeat protein 2) (F-box protein FBL2/FBL3)

Gene: FBXL2
Organism: Homo sapiens
Interactions: 37
UniProt ID: Q9UKC9

Gene Ontology (top 5):
GO:0005516 - calmodulin binding
GO:0005737 - cytoplasm
GO:0006508 - proteolysis
GO:0006513 - protein monoubiquitination
GO:0010506 - regulation of autophagy

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

929111

SKP1
S-phase kinase-associated protein 1

14

20

Small-scale

0.982

High

1041267

CUL1
Cullin-1

7

20

Small-scale

0.956

High

1299042

NLRP3
NACHT, LRR and PYD domains-containing protein 3

2

9

Small-scale

0.825

High

1356338

FBX3
F-box only protein 3

3

0

Small-scale

0.784

High

1292283

AURKB
Aurora kinase B

2

3

Small-scale

0.746

High

1055817

ITPR3
Inositol 1,4,5-trisphosphate receptor type 3

3

1

Small-scale

0.664

High

1041495

CUL2
Cullin-2

1

20

Small-scale

0.618

High

828052

UB2R1
Ubiquitin-conjugating enzyme E2 R1

2

8

Small-scale

0.602

High

895948

UB2D3
Ubiquitin-conjugating enzyme E2 D3

2

4

Small-scale

0.602

High

993355

FOXM1
Forkhead box protein M1

3

1

Small-scale

0.599

High

238760

YPEL1
Protein yippee-like 1

2

3

High-throughput

0.574

High

898088

YPEL3
Protein yippee-like 3

2

3

High-throughput

0.574

High

438607

HS90B
Heat shock protein HSP 90-beta

2

14

High-throughput

0.571

High

129346

P85B
Phosphatidylinositol 3-kinase regulatory subunit beta

1

3

Small-scale

0.561

High

339114

EGFR
Epidermal growth factor receptor

1

17

Small-scale

0.561

High

396024

A4
Amyloid-beta precursor protein

1

3

Small-scale

0.561

High

673112

CCND2
G1/S-specific cyclin-D2

1

8

Small-scale

0.561

High

500200

CH60
60 kDa heat shock protein, mitochondrial

1

2

High-throughput

0.515

High

849483

UB2D1
Ubiquitin-conjugating enzyme E2 D1

1

4

Small-scale

0.501

High

921472

RBX1
E3 ubiquitin-protein ligase RBX1

1

7

Small-scale

0.501

High

217743

PDE6D
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta

1

1

Small-scale

0.479

High

432349

HS90A
Heat shock protein HSP 90-alpha

1

12

High-throughput

0.479

High

655497

P85A
Phosphatidylinositol 3-kinase regulatory subunit alpha

1

1

Small-scale

0.479

High

853513

IMA1
Importin subunit alpha-1

1

3

High-throughput

0.479

High

863140

PGTB2
Geranylgeranyl transferase type-2 subunit beta

1

1

Small-scale

0.479

High

875417

TERA
Transitional endoplasmic reticulum ATPase

1

2

Small-scale

0.479

High

968120

SC6A3
Sodium-dependent dopamine transporter

1

1

Small-scale

0.479

High

1336111

SMUF1
E3 ubiquitin-protein ligase SMURF1

1

9

Small-scale

0.479

High

821458

TCPE
T-complex protein 1 subunit epsilon

1

2

High-throughput

0.470

High

1020234

PTN13
Tyrosine-protein phosphatase non-receptor type 13

1

0

Small-scale

0.458

High

908272

UB2G1
Ubiquitin-conjugating enzyme E2 G1

1

6

Small-scale

0.457

High

738112

PP1G
Serine/threonine-protein phosphatase PP1-gamma catalytic subunit

1

6

Small-scale

0.457

High

1356393

SGT1
Protein SGT1 homolog

1

11

High-throughput

0.407

High

353019

IL1B
Interleukin-1 beta

1

0

Small-scale

0.261

Low

1217780

FUND1
FUN14 domain-containing protein 1

1

0

Small-scale

0.249

Low

1349541

HACD3
Very-long-chain

1

0

Small-scale

0.249

Low

970678

CO7A1
Collagen alpha-1(VII) chain

1

0

High-throughput

0.238

Low


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Last updated: 15 Jul 2024