Interactor 1: THRB (P00734)
Prothrombin (EC 3.4.21.5) (Coagulation factor II) [Cleaved into: Activation peptide fragment 1; Activation peptide fragment 2; Thrombin light chain; Thrombin heavy chain]
Gene: F2
Interactor 2: FA10 (P00742)
Coagulation factor X (EC 3.4.21.6) (Stuart factor) (Stuart-Prower factor) [Cleaved into: Factor X light chain; Factor X heavy chain; Activated factor Xa heavy chain]
Gene: F10
Species: Homo sapiens
Source: biogrid
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.58 | 1.00 | 0.768 |
The method score is based on:
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | Kringle~Trypsin, Thrombin_light~Trypsin, EGF~Trypsin, FXa_inhibition~Trypsin, Trypsin~Trypsin |
| Common GO terms | GO:0004252 - serine-type endopeptidase activity GO:0005509 - calcium ion binding GO:0005576 - extracellular region GO:0005615 - extracellular space GO:0005788 - endoplasmic reticulum lumen and 4 others more... |
| Homologous interactions | 16 |
Homologous interactions
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
