Interactor 1: FA10 (P00742)
Coagulation factor X (EC 3.4.21.6) (Stuart factor) (Stuart-Prower factor) [Cleaved into: Factor X light chain; Factor X heavy chain; Activated factor Xa heavy chain]
Gene: F10
Interactor 2: TPA (P00750)
Tissue-type plasminogen activator (t-PA) (t-plasminogen activator) (tPA) (EC 3.4.21.68) (Alteplase) (Reteplase) [Cleaved into: Tissue-type plasminogen activator chain A; Tissue-type plasminogen activator chain B]
Gene: PLAT
Species: Homo sapiens
Source: biogrid
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.41 | 1.00 | 0.647 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 11371191 |
| Identification Methods | pull down |
| Interaction Type | direct interaction |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | EGF~EGF, EGF~fn1, EGF~Trypsin, EGF~FXa_inhibition, FXa_inhibition~Trypsin, Kringle~Trypsin, Trypsin~Trypsin |
| Common GO terms | GO:0004252 - serine-type endopeptidase activity GO:0005576 - extracellular region GO:0005615 - extracellular space GO:0006508 - proteolysis GO:0007596 - blood coagulation |
| Homologous interactions | 15 |
Homologous interactions
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
