Interactor 1: FA10 (P00742)
Coagulation factor X (EC 3.4.21.6) (Stuart factor) (Stuart-Prower factor) [Cleaved into: Factor X light chain; Factor X heavy chain; Activated factor Xa heavy chain]
Gene: F10

Interactor 2: ZPI (Q9UK55)
Protein Z-dependent protease inhibitor (PZ-dependent protease inhibitor) (PZI) (Serpin A10)
Gene: SERPINA10

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.47 1.00 0.692

The method score is based on:

Property Details
Experiments 20427285
Identification Methods affinity technology, comigration in non denaturing gel electrophoresis
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains FXa_inhibition~Serpin, Serpin~Trypsin
Common GO terms GO:0005615 - extracellular space
GO:0005788 - endoplasmic reticulum lumen
GO:0007596 - blood coagulation
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 488
Hs

1 444
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024