HitPredict

Interactor 1: A1AT (P01009)
Alpha-1-antitrypsin (Alpha-1 protease inhibitor) (Alpha-1-antiproteinase) (Serpin A1) [Cleaved into: Short peptide from AAT (SPAAT)]
Gene: SERPINA1

Interactor 2: SOX2 (P48431)
Transcription factor SOX-2
Gene: SOX2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	34732716
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 418 Hs			1 317
+	Hs
		818224 SPA12_HUMAN (1-418): 1e-153: 442: 38.28		SOX2_HUMAN (1-317): 2.16e-77: 240: 100.00
+	Hs
		397016 PAI2_HUMAN (50-415): 9.67e-149: 430: 28.88		SOX2_HUMAN (1-317): 2.16e-77: 240: 100.00
+	Hs
		675627 ILEU_HUMAN (49-415): 2.65e-145: 420: 29.92		SOX2_HUMAN (1-317): 2.16e-77: 240: 100.00
+	Hs
		817802 SPB8_HUMAN (48-415): 1.46e-145: 420: 31.48		SOX2_HUMAN (1-317): 2.16e-77: 240: 100.00
+	Hs
		344108 ANT3_HUMAN (17-418): 4.53e-142: 415: 28.40		SOX2_HUMAN (1-317): 2.16e-77: 240: 100.00
+	Hs
		818577 SPB13_HUMAN (48-415): 1.51e-143: 415: 28.65		SOX2_HUMAN (1-317): 2.16e-77: 240: 100.00
+	Hs
		271857 SPB7_HUMAN (48-415): 3.68e-139: 404: 26.96		SOX2_HUMAN (1-317): 2.16e-77: 240: 100.00
+	Hs
		331681 A1AT_HUMAN (1-418): 0: 521: 100.00		NSD2_HUMAN (7-251): 1.34e-29: 120: 10.71
+	Hs
		397097 PAI1_HUMAN (38-415): 7.3e-137: 399: 28.17		SOX2_HUMAN (1-317): 2.16e-77: 240: 100.00
+	Hs
		818366 SPB12_HUMAN (48-415): 3.78e-135: 394: 28.47		SOX2_HUMAN (1-317): 2.16e-77: 240: 100.00
+	Hs
		331682 AACT_HUMAN (20-417): 3e-164: 469: 43.56		NSD2_HUMAN (7-251): 1.34e-29: 120: 10.71
+	Hs
		668017 SPB3_HUMAN (48-415): 1.73e-147: 425: 31.03		CIC_HUMAN (3-272): 8.9e-33: 130: 22.26