HitPredict

Interactor 1: A1AT (P01009)
Alpha-1-antitrypsin (Alpha-1 protease inhibitor) (Alpha-1-antiproteinase) (Serpin A1) [Cleaved into: Short peptide from AAT (SPAAT)]
Gene: SERPINA1

Interactor 2: SLX4 (Q8IY92)
Structure-specific endonuclease subunit SLX4 (BTB/POZ domain-containing protein 12)
Gene: SLX4

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.50	0.521

Property	Details
Experiments	37059091, 19596235
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 418 Hs			1 1834
+	Hs
		820336 SPB4_HUMAN (48-415): 1.16e-148: 428: 32.31		SLX4_HUMAN (1-1834): 0: 1486: 100.00
+	Hs
		667995 SPB3_HUMAN (48-415): 1.73e-147: 425: 31.03		SLX4_HUMAN (1-1834): 0: 1486: 100.00
+	Hs
		1222527 SPB12_HUMAN (48-415): 3.78e-135: 394: 28.47		SLX4_HUMAN (1-1834): 0: 1486: 100.00
+	Hs
		801019 SPB4_HUMAN (48-415): 1.16e-148: 428: 32.31		KI67_HUMAN (889-1833): 3.44e-23: 110: 10.79
+	Hs
		271856 SPB7_HUMAN (48-415): 3.68e-139: 404: 26.96		KI67_HUMAN (889-1833): 3.44e-23: 110: 10.79