Interactor 1: ANGT (P01019)
Angiotensinogen (Serpin A8) [Cleaved into: Angiotensin-1 (Angiotensin 1-10) (Angiotensin I) (Ang I); Angiotensin-2 (Angiotensin 1-8) (Angiotensin II) (Ang II); Angiotensin-3 (Angiotensin 2-8) (Angiotensin III) (Ang III) (Des-Asp[1]-angiotensin II); Angiotensin-4 (Angiotensin 3-8) (Angiotensin IV) (Ang IV); Angiotensin 1-9; Angiotensin 1-7; Angiotensin 1-5; Angiotensin 1-4]
Gene: AGT

Interactor 2: AGTR1 (P30556)
Type-1 angiotensin II receptor (AT1AR) (AT1BR) (Angiotensin II type-1 receptor) (AT1 receptor)
Gene: AGTR1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 0.60 0.479

The method score is based on:

Property Details
Experiments 23597562
Identification Methods scintillation proximity assay
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0001558 - regulation of cell growth
GO:0001822 - kidney development
GO:0002018 - renin-angiotensin regulation of aldosterone production
GO:0002034 - maintenance of blood vessel diameter homeostasis by renin-angiotensin
GO:0007186 - G protein-coupled receptor signaling pathway
and 11 others

more...

Homologous interactions 12

Homologous interactions

Color coding for hit scores

1 476
Hs

1 359
+ Rn
+ Mm
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs

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Last updated: 15 Jul 2024