Interactor 1: A2MG (P01023)
Alpha-2-macroglobulin (Alpha-2-M) (C3 and PZP-like alpha-2-macroglobulin domain-containing protein 5)
Gene: A2M
Interactor 2: A2MG (P01023)
Alpha-2-macroglobulin (Alpha-2-M) (C3 and PZP-like alpha-2-macroglobulin domain-containing protein 5)
Gene: A2M
Species: Homo sapiens
Source: biogrid
Category: High-throughput
Confidence: High
Method score | Annotation score | Interaction score |
---|---|---|
0.38 | 1.00 | 0.621 |
The method score is based on:
Property | Details |
---|---|
Experiments | 21163940 |
Identification Methods | two hybrid |
Interaction Type | direct interaction |
The annotation score is based on:
Property | Details |
---|---|
Interacting Pfam domains | A2M~A2M_BRD, A2M~A2M_recep, A2M~MG2, A2M~MG3, A2M_BRD~A2M_BRD, A2M_BRD~MG2, A2M_BRD~MG3, A2M_BRD~MG4, A2M_recep~A2M_recep, A2M_recep~MG3, A2M_recep~TED_complement, MG2~MG2, MG2~MG3, MG2~TED_complement, MG3~MG3, MG3~MG4, MG3~TED_complement, MG4~MG4, MG4~TED_complement, TED_complement~TED_complement |
Common GO terms | GO:0001553 - luteinization GO:0001869 - negative regulation of complement activation, lectin pathway GO:0002020 - protease binding GO:0002438 - acute inflammatory response to antigenic stimulus GO:0004866 - endopeptidase inhibitor activity and 23 others more... |
Homologous interactions | 3 |
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Last updated: 15 Jul 2024