HitPredict

Interactor 1: A2MG (P01023)
Alpha-2-macroglobulin (Alpha-2-M) (C3 and PZP-like alpha-2-macroglobulin domain-containing protein 5)
Gene: A2M

Interactor 2: TAU (P10636)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: MAPT

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.50	0.60	0.552

Property	Details
Experiments	26402096, 35063084
Identification Methods	anti bait coimmunoprecipitation, anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005576 - extracellular region GO:0019899 - enzyme binding
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1 1474 Hs			1 758
+	Hs
		496286 PZP_HUMAN (24-1470): 0: 1806: 72.41		TAU_HUMAN (1-758): 3.6e-89: 298: 100.00
+	Hs
		344627 CO3_HUMAN (27-1464): 0: 1294: 22.43		TAU_HUMAN (1-758): 3.6e-89: 298: 100.00
+	Hs
		469898 CO4B_HUMAN (23-1471): 0: 1278: 22.97		TAU_HUMAN (1-758): 3.6e-89: 298: 100.00