HitPredict

Interactor 1: INS (P01308)
Insulin [Cleaved into: Insulin B chain; Insulin A chain]
Gene: INS

Interactor 2: THIO (P10599)
Thioredoxin (Trx) (ATL-derived factor) (ADF) (Surface-associated sulphydryl protein) (SASP) (allergen Hom s Trx)
Gene: TXN

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	32457219
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005576 - extracellular region GO:0032148 - activation of protein kinase B activity GO:0051897 - positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1 110 Hs			1 105
+	Hs
		202573 INS_HUMAN (1-110): 3.37e-65: 194: 100.00		TXNL1_HUMAN (2-105): 1.99e-36: 126: 40.39
+	Hs
		352187 INS_HUMAN (1-110): 3.37e-65: 194: 100.00		TXND5_HUMAN (12-105): 2.13e-27: 105: 27.00
+	Hs
		351890 INS_HUMAN (1-110): 3.37e-65: 194: 100.00		PDIA1_HUMAN (2-103): 7.44e-23: 92.9: 22.22