Interactor 1: CO3 (P01024)
Complement C3 (C3 and PZP-like alpha-2-macroglobulin domain-containing protein 1) [Cleaved into: Complement C3 beta chain; C3-beta-c (C3bc); Complement C3 alpha chain; C3a anaphylatoxin; Acylation stimulating protein (ASP) (C3adesArg); Complement C3b alpha' chain; Complement C3c alpha' chain fragment 1; Complement C3dg fragment; Complement C3g fragment; Complement C3d fragment; Complement C3f fragment; Complement C3c alpha' chain fragment 2]
Gene: C3

Interactor 2: CATG (P08311)
Cathepsin G (CG) (EC 3.4.21.20) [Cleaved into: Cathepsin G, C-terminal truncated form]
Gene: CTSG

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 24355864
Identification Methods enzyme linked immunosorbent assay
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains A2M_recep~Trypsin, MG1~Trypsin, MG2~Trypsin
Common GO terms GO:0005576 - extracellular region
GO:0005615 - extracellular space
GO:0005886 - plasma membrane
GO:0006955 - immune response
GO:0035578 - azurophil granule lumen
and 1 others

more...

Homologous interactions 7

Homologous interactions

Color coding for hit scores

1 1663
Hs

1 255
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Last updated: 15 Jul 2024