HitPredict

Interactor 1: KNG1 (P01042)
Kininogen-1 (Alpha-2-thiol proteinase inhibitor) (Fitzgerald factor) (High molecular weight kininogen) (HMWK) (Williams-Fitzgerald-Flaujeac factor) [Cleaved into: Kininogen-1 heavy chain; T-kinin (Ile-Ser-Bradykinin); Bradykinin (Kallidin I); Lysyl-bradykinin (Kallidin II); Kininogen-1 light chain; Low molecular weight growth-promoting factor]
Gene: KNG1

Interactor 2: TBB8 (Q3ZCM7)
Tubulin beta-8 chain (Tubulin beta 8 class VIII)
Gene: TUBB8

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	26186194, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0070062 - extracellular exosome
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 644 Hs			1 444
+	Hs
		238486 CST8_HUMAN (238-374): 1.93e-36: 135: 18.84		TBB3_HUMAN (1-442): 0: 719: 86.43
+	Hs
		1037387 CSTL1_HUMAN (267-370): 1.14e-35: 132: 20.00		TBB3_HUMAN (1-442): 0: 719: 86.43
+	Hs
		238490 CST8_HUMAN (238-374): 1.93e-36: 135: 18.84		TBB8_HUMAN (1-427): 0: 708: 100.00
+	Hs
		428424 CST11_HUMAN (269-373): 2.03e-32: 123: 20.76		TBB5_HUMAN (1-429): 0: 720: 89.74
+	Hs
		1037386 CST11_HUMAN (269-373): 2.03e-32: 123: 20.76		TBB3_HUMAN (1-442): 0: 719: 86.43
+	Hs
		381295 CST11_HUMAN (269-373): 2.03e-32: 123: 20.76		TBB4A_HUMAN (1-427): 0: 715: 90.16
+	Hs
		1114229 CST11_HUMAN (269-373): 2.03e-32: 123: 20.76		TBB8_HUMAN (1-427): 0: 708: 100.00