HitPredict

Interactor 1: FOS (P01100)
Protein c-Fos (Cellular oncogene fos) (Fos proto-oncogene, AP-1 transcription factor subunit) (G0/G1 switch regulatory protein 7) (Proto-oncogene c-Fos) (Transcription factor AP-1 subunit c-Fos)
Gene: FOS

Interactor 2: MMP9 (P14780)
Matrix metalloproteinase-9 (MMP-9) (EC 3.4.24.35) (92 kDa gelatinase) (92 kDa type IV collagenase) (Gelatinase B) (GELB) [Cleaved into: 67 kDa matrix metalloproteinase-9; 82 kDa matrix metalloproteinase-9]
Gene: MMP9

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	18028425
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0034614 - cellular response to reactive oxygen species GO:0071276 - cellular response to cadmium ion
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 380 Hs			1 707
+	Hs
		540410 JUND_HUMAN (112-215): 1.79e-13: 72.8: 20.00		MMP9_HUMAN (1-707): 0: 862: 100.00
+	Hs
		345361 FOS_HUMAN (1-380): 1.68e-84: 263: 100.00		MMP13_HUMAN (1-277): 5.97e-98: 311: 35.15
+	Hs
		345276 FOS_HUMAN (1-380): 1.68e-84: 263: 100.00		MMP1_HUMAN (31-238): 9.64e-87: 282: 42.67
+	Hs
		401589 JUN_HUMAN (48-215): 1.19e-23: 102: 16.47		MMP13_HUMAN (1-277): 5.97e-98: 311: 35.15
+	Hs
		372725 FOSL1_HUMAN (59-287): 1.43e-34: 130: 37.61		MMP1_HUMAN (31-238): 9.64e-87: 282: 42.67
+	Hs
		372729 ATF3_HUMAN (131-215): 4.23e-25: 102: 43.53		MMP1_HUMAN (31-238): 9.64e-87: 282: 42.67
+	Mm
		345605 FOS_MOUSE (1-380): 1.27e-84: 263: 93.68		MMP13_MOUSE (576-703): 1.34e-15: 82.1: 15.91