Interactor 1: FOS (P01101)
Protein c-Fos (Cellular oncogene fos) (FBJ osteosarcoma oncogene) (Transcription factor AP-1 subunit c-Fos)
Gene: FOS

Interactor 2: TNFA (P06804)
Tumor necrosis factor (Cachectin) (TNF-alpha) (Tumor necrosis factor ligand superfamily member 2) (TNF-a) [Cleaved into: Tumor necrosis factor, membrane form (N-terminal fragment) (NTF); Intracellular domain 1 (ICD1); Intracellular domain 2 (ICD2); C-domain 1; C-domain 2; Tumor necrosis factor, soluble form]
Gene: Tnf

Species: Mus musculus

Source: innatedb

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.60 0.60 0.601

The method score is based on:

Property Details
Experiments 19285436, 25548221
Identification Methods anti tag coimmunoprecipitation, affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0009410 - response to xenobiotic stimulus
GO:0014823 - response to activity
GO:0030316 - osteoclast differentiation
GO:0032496 - response to lipopolysaccharide
GO:0045471 - response to ethanol
and 3 others

more...

Homologous interactions 5

Homologous interactions

Color coding for hit scores

1 380
Mm

1 235
+ Mm
+ Hs
+ Mm
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024