HitPredict

Interactor 1: MYC (P01106)
Myc proto-oncogene protein (Class E basic helix-loop-helix protein 39) (bHLHe39) (Proto-oncogene c-Myc) (Transcription factor p64)
Gene: MYC

Interactor 2: RASN (P01111)
GTPase NRas (EC 3.6.5.2) (Transforming protein N-Ras)
Gene: NRAS

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	36424410
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000165 - MAPK cascade GO:0044877 - protein-containing complex binding
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 454 Hs			1 189
+	Hs
		346439 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		RAB1A_HUMAN (4-187): 1.35e-76: 229: 33.33
+	Hs
		347860 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		RAB1B_HUMAN (4-187): 1.35e-75: 226: 33.51
+	Hs
		346383 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		RAB14_HUMAN (4-185): 2.1e-73: 221: 29.35
+	Hs
		345787 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		RALA_HUMAN (4-169): 7.15e-59: 184: 53.89
+	Hs
		297806 K0754_HUMAN (47-360): 3.79e-40: 156: 12.62		RASK_HUMAN (16-189): 7.56e-85: 249: 85.71
+	Hs
		297829 K0754_HUMAN (47-360): 3.79e-40: 156: 12.62		RAB35_HUMAN (4-171): 6.96e-84: 247: 34.71
+	Hs
		297805 K0754_HUMAN (47-360): 3.79e-40: 156: 12.62		RASN_HUMAN (1-189): 9.9e-80: 236: 100.00
+	Hs
		349126 USF1_HUMAN (175-453): 1.02e-39: 146: 18.40		RASH_HUMAN (1-188): 8.6e-78: 232: 85.64
+	Hs
		1016067 SRBP2_HUMAN (124-446): 8.64e-35: 139: 12.54		RB11B_HUMAN (4-184): 2.97e-73: 221: 32.79