HitPredict

Interactor 1: MYC (P01106)
Myc proto-oncogene protein (Class E basic helix-loop-helix protein 39) (bHLHe39) (Proto-oncogene c-Myc) (Transcription factor p64)
Gene: MYC

Interactor 2: HSPB1 (P04792)
Heat shock protein beta-1 (HspB1) (28 kDa heat shock protein) (Estrogen-regulated 24 kDa protein) (Heat shock 27 kDa protein) (HSP 27) (Heat shock protein family B member 1) (Stress-responsive protein 27) (SRP27)
Gene: HSPB1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.84	0.60	0.714

Property	Details
Experiments	29467282, 35013218, 36424410, 17314511, 21150319
Identification Methods	affinity chromatography technology, proximity labelling technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0043066 - negative regulation of apoptotic process
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 454 Hs			1 205
+	Hs
		348187 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		HSPB8_HUMAN (1-180): 1.08e-42: 143: 37.17
+	Hs
		378895 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		HSPB1_HUMAN (1-205): 4.5e-80: 239: 100.00
+	Hs
		388350 MAX_HUMAN (354-454): 1.39e-24: 101: 32.67		HSPB1_HUMAN (1-205): 4.5e-80: 239: 100.00
+	Hs
		1080875 MGAP_HUMAN (151-449): 1.22e-27: 118: 17.71		HSPB2_HUMAN (1-181): 2.16e-45: 150: 35.52
+	Hs
		898129 MAX_HUMAN (354-454): 1.39e-24: 101: 32.67		HSPB2_HUMAN (1-181): 2.16e-45: 150: 35.52