HitPredict

Interactor 1: MYC (P01106)
Myc proto-oncogene protein (Class E basic helix-loop-helix protein 39) (bHLHe39) (Proto-oncogene c-Myc) (Transcription factor p64)
Gene: MYC

Interactor 2: GNAI2 (P04899)
Guanine nucleotide-binding protein G(i) subunit alpha-2 (Adenylate cyclase-inhibiting G alpha protein)
Gene: GNAI2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	29467282, 35013218
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0008284 - positive regulation of cell population proliferation
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 454 Hs			1 355
+	Hs
		345741 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		GNAI3_HUMAN (1-355): 1.01e-174: 490: 85.92
+	Hs
		345888 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		GNAT2_HUMAN (1-355): 1.04e-166: 470: 69.86
+	Hs
		346463 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		GNAS2_HUMAN (1-355): 1.94e-147: 423: 38.83
+	Hs
		378897 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		GNAI2_HUMAN (1-355): 8.42e-180: 504: 100.00