Interactor 1: BAG3 (O95817)
BAG family molecular chaperone regulator 3 (BAG-3) (Bcl-2-associated athanogene 3) (Bcl-2-binding protein Bis) (Docking protein CAIR-1)
Gene: BAG3
Interactor 2: HSPB1 (P04792)
Heat shock protein beta-1 (HspB1) (28 kDa heat shock protein) (Estrogen-regulated 24 kDa protein) (Heat shock 27 kDa protein) (HSP 27) (Heat shock protein family B member 1) (Stress-responsive protein 27) (SRP27)
Gene: HSPB1
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.90 | 0.60 | 0.739 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 25277244, 26496610, 30559338, 35066290, 25036637, 32814053 |
| Identification Methods | two hybrid, affinity chromatography technology, pull down, two hybrid array, two hybrid pooling approach, reverse ras recruitment system, anti tag coimmunoprecipitation, validated two hybrid, luminescence based mammalian interactome mapping |
| Interaction Type | direct interaction, physical association, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | - |
| Common GO terms | GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0030018 - Z disc GO:0043066 - negative regulation of apoptotic process |
| Homologous interactions | 9 |
Homologous interactions
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
