HitPredict

Interactor 1: MYC (P01106)
Myc proto-oncogene protein (Class E basic helix-loop-helix protein 39) (bHLHe39) (Proto-oncogene c-Myc) (Transcription factor p64)
Gene: MYC

Interactor 2: CK5P2 (Q96SN8)
CDK5 regulatory subunit-associated protein 2 (CDK5 activator-binding protein C48) (Centrosome-associated protein 215)
Gene: CDK5RAP2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	21150319
Identification Methods	tandem affinity purification
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0044877 - protein-containing complex binding GO:0045893 - positive regulation of DNA-templated transcription
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 454 Hs			1 1893
+	Hs
		346711 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		GOGA4_HUMAN (1-1777): 1.29e-60: 233: 10.50
+	Hs
		345802 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		TPR_HUMAN (1-749): 1.76e-27: 124: 10.95
+	Hs
		345843 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		DESP_HUMAN (35-576): 3.93e-27: 123: 16.16
+	Hs
		346088 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		MYH9_HUMAN (1076-1870): 2.72e-24: 114: 10.17
+	Hs
		347019 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		MRCKA_HUMAN (51-491): 8.55e-24: 112: 14.26
+	Hs
		346097 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		MYH11_HUMAN (1-610): 8.41e-23: 109: 13.33
+	Hs
		347982 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		MYO5C_HUMAN (103-604): 2.19e-16: 88: 18.67
+	Hs
		347472 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		MY18A_HUMAN (124-716): 5.89e-15: 83.4: 16.56
+	Hs
		346089 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		MYH10_HUMAN (1278-1866): 8.19e-15: 83: 11.48
+	Hs
		378961 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		TPR_HUMAN (1-749): 1.76e-27: 124: 10.95
+	Hs
		378986 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		DESP_HUMAN (35-576): 3.93e-27: 123: 16.16
+	Hs
		1016064 SRBP2_HUMAN (124-446): 8.64e-35: 139: 12.54		GOGB1_HUMAN (1-1241): 3.09e-44: 180: 9.91
+	Hs
		379070 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		MYH9_HUMAN (1076-1870): 2.72e-24: 114: 10.17
+	Hs
		379071 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		MYH10_HUMAN (1278-1866): 8.19e-15: 83: 11.48
+	Hs
		518915 MNT_HUMAN (274-452): 2.36e-24: 107: 21.11		TPR_HUMAN (1-749): 1.76e-27: 124: 10.95