HitPredict

Interactor 1: MYC (P01106)
Myc proto-oncogene protein (Class E basic helix-loop-helix protein 39) (bHLHe39) (Proto-oncogene c-Myc) (Transcription factor p64)
Gene: MYC

Interactor 2: SMRCD (Q9H4L7)
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1 (EC 3.6.4.12) (ATP-dependent helicase 1) (hHEL1)
Gene: SMARCAD1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	29467282, 17353931
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003677 - DNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0006338 - chromatin remodeling
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 454 Hs			1 1026
+	Hs
		346268 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		SMCA4_HUMAN (96-1024): 0: 693: 26.54
+	Hs
		346267 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		SMCA2_HUMAN (55-1024): 0: 689: 25.05
+	Hs
		348113 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		CHD7_HUMAN (23-1021): 0: 683: 22.57
+	Mm
		348422 MYC_MOUSE (1-454): 4.33e-119: 357: 89.01		SMCA4_MOUSE (96-1024): 0: 692: 26.43
+	Hs
		346938 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		CHD9_HUMAN (79-1021): 0: 651: 22.17
+	Hs
		347951 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		CHD8_HUMAN (181-1021): 0: 641: 23.28
+	Hs
		347406 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		CHD5_HUMAN (338-1022): 0: 629: 27.78
+	Hs
		346581 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		ERCC6_HUMAN (21-1021): 0: 595: 20.53
+	Hs
		151469 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		CHD2_HUMAN (33-1022): 0: 594: 22.15
+	Hs
		229271 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		SMCA5_HUMAN (353-1021): 0: 594: 29.60
+	Hs
		346003 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		SMCA1_HUMAN (379-1021): 0: 590: 29.56
+	Hs
		379142 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		SMCA4_HUMAN (96-1024): 0: 693: 26.54
+	Hs
		379141 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		SMCA2_HUMAN (55-1024): 0: 689: 25.05
+	Hs
		379973 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		CHD7_HUMAN (23-1021): 0: 683: 22.57
+	Hs
		151473 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		CHD2_HUMAN (33-1022): 0: 594: 22.15
+	Hs
		229276 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		SMCA5_HUMAN (353-1021): 0: 594: 29.60
+	Hs
		607839 USF1_HUMAN (175-453): 1.02e-39: 146: 18.40		CHD8_HUMAN (181-1021): 0: 641: 23.28
+	Hs
		229308 USF1_HUMAN (175-453): 1.02e-39: 146: 18.40		SMCA5_HUMAN (353-1021): 0: 594: 29.60
+	Hs
		607786 USF1_HUMAN (175-453): 1.02e-39: 146: 18.40		SMCA1_HUMAN (379-1021): 0: 590: 29.56
+	Hs
		348000 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		HELLS_HUMAN (479-999): 1.2e-93: 318: 37.59